BACKGROUND Coumarin and their derivatives are important and useful compounds with diverse pharmacological properties. In the present study, we evaluated the in vitro cytotoxic activity of new acetoxycoumarin derivatives: 4-(7-methoxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate (1), 4-(1-methyl-3-oxo-3H-benzo[f]chromen-2-yl)phenyl acetate (2), 4-(6-propionamido-4-methyl-2-oxo-2H-chromen-3-yl) ...

Reactions of hydrazonoyl halides and each of methyl 2-(1-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)ethylidene)hydrazine-1-carbodithioate and 2-(1-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)ethylidene)hydrazine-1-carbothioamide afforded 2-(1-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)ethylidene)hydrazono)-3-phenyl-5-substituted-2,3-dihydro-1,3,4-thiadiazoles and 5-(4-substituted)diazenyl)-2-(2-(1-(5-...

in this research, an efficient synthesis toward 2-(2-((4-methoxybenzoyl)imino)-4-(4-methoxyphenyl)thiazol-3(2h)-yl)-2-phenylacetic acid via a three-component tandem reaction using aroylisothiocyanate, phenyl glycine, and 4-methoxyphenacyl bromide in an ionic liquid (il) has been described. 1-methyl-3-pentylimidazolium bromide (il) has been employed as a recyclable green solvent. the work-up pro...

Photoionization cross sections of the phenyl radical to form the phenyl cation were measured using tunable vacuum ultraviolet synchrotron radiation coupled with photofragment translational spectroscopy. The phenyl radical was produced via 193- or 248-nm dissociation of chlorobenzene. At 10.0 eV, the photoionization cross sections for the phenyl radical averaged over product channels were found ...

In the title compound, C(20)H(13)ClO(2)S, the O atom and the phenyl group of the phenyl-sulfinyl substituent lie on opposite sides of the plane of the benzofuran fragment; the S-bound phenyl ring is nearly perpendicular to this plane [80.87 (5)°]. The phenyl ring in the 2-position is rotated out of the benzofuran plane, making a dihedral angle of 17.43 (7)°. The crystal structure features π-π i...

In the crystal structure of the title compound, C(28)H(29)FN(4)O(2)S, the imidazole ring makes dihedral angles of 11.85 (7), 73.33 (7) and 22.83 (8)° with the 4-fluoro-phenyl, pyridine and phenyl rings, respectively. The 4-fluoro-phenyl ring makes dihedral angles of 77.91 (7) and 26.93 (8)° with the pyridine and phenyl rings, respectively. The phenyl and pyridine rings are nearly perpendicular,...

The reactions of the phenyl radical (C6H5) with 1-butyne (HCCC2H5) and 2-butyne (CH3CCCH3) were studied in a crossed molecular beam machine to shed light on the formation of C10H10 isomers in combustion flames. Combining these data with electronic structure calculations, we find that both reactions involve indirect scattering dynamics and are initiated by additions of the phenyl radical with it...

The title compound, C30H28N2, is a product of the condensation reaction of 2-methyl-4-phenyl-aniline and butane-2,3-dione. The mol-ecule lies on a crystallographic inversion centre. The C=N bond has an E conformation. The dihedral angle between the two benzene rings of the 4-phenyl-2-methyl-phenyl group is 29.19 (76)°. The 1,4-di-aza-butadiene plane makes an angle of 70.1 (10)° with the N-bonde...

A DFT/TDDFT investigation was carried out on a series of homoleptic triphenylamine-featured Ir(iii) complexes [: (fac-tris[2-phenyl-4-(2-(N,N-diphenylamino)phenyl)pyridine]iridium(iii)); : (fac-tris[2-phenyl-4-(3-(N,N-diphenylamino)phenyl)pyridine]iridium(iii)); : (fac-tris[2-phenyl-4-(4-(N,N-diphenylamino)phenyl)pyridine]iridium(iii))] with one triphenylamine unit in the 2-phenylpyridine (ppy)...

6-methyl- 1,2,4-triazine-3-(2h)-selenone-5(4h)-one(l) reacts in the presence of base with phenacyl bromide to give a mixture of compounds (2) and (3). this mixture is dehydrated in the presence of h,so, to give 3-phenyl-6 methyl-7h-selenazolo[3,2-b] [i ,2,4] triazin-7-one (6). for careful structure assignment of (6) its regioisomer 3-methyl-6-phenyl-4h-selenazolo [2,3-c] [ 1,2,4] triazin-4-one ...