Dose-response curves for inactivation of synchronized cells from the human cell line NHK 3025 in the presence of hematoporphyrin and light are shown. Sensitivity toward photodynamic inactivation is increasing as the cells move in the cell cycle from G1 to mid-S. The increase is mostly due to a change in the extent of the shoulder of the dose-response curve at low doses. The quasithreshold dose ...

Chlorin-e6 (chl-e6) and a hydrogenated derivative (chl-e6H) were semi-synthesized, and their photophysical properties and photodynamic activity against Escherichia coli, Staphylococcus aureus and Candida albicans evaluated. Methyl pheophorbide-a (Mepheo-a) was obtained from S. maxima using methanolic extraction with acid catalysis (CH3OH–H2SO4). Chlorin-e6 was prepared from Mepheo-a by basic hy...

Abstract In recent years, multifunctional nanoparticles with combined diagnostic and therapeutic functions show great promise in nanomedicine. this study, we report the environmentally friendly synthesis of fluorescent carbon nano-dots such as quantum dots (CQDs) by microplasma using o -phenylenediamine. The produced CQDs exhibited a wide absorption peaks at 380–500 nm emitted bright yellow flu...

The photodynamic inactivation of the membrane functions of bacteria was analyzed in situ, using K(+) and tetraphenylphosphonium (TPP(+)) electrodes, as well as an oxygen electrode. Tetrakis(4-N-trimethylaminophenyl)porphine (TTMAPP) and rose bengal were used, since both dyes act strongly on bacteria, such as Staphylococcus aureus. After a short time lag, they inhibited the respiration of bacter...

We develop an accurate finite-time scaling analysis of the angular width of the coherent backscattering (CBS) peak for waves propagating in 3D random media. Applying this method to ultracold atoms in optical speckle potentials, we show how to determine both the mobility edge and the critical exponent of the Anderson transition from the temporal behavior of the CBS width. Our method could be use...

Coherent backscattering (CBS) of light in random media has been previously investigated by use of coherent light sources. Here we report a novel method of CBS measurement that combines low spatial coherence, broadband illumination, and spectrally resolved detection. We show that low spatial coherence illumination leads to an anomalously broad CBS peak and a dramatic speckle reduction; the latte...