PURPOSE To evaluate the safety and efficacy of intrastromal corneal ring segments (ICRS) implantation followed by same-day topography-guided photorefractive keratectomy (PRK) and ultraviolet-A/riboflavin collagen cross-linking (CXL) in patients with low to moderate keratoconus. METHODS Patients with low to moderate keratoconus and contact lens intolerance were included in the study. All patie...

PURPOSE To evaluate short-term changes in central corneal endothelial cell density and morphology after photorefractive keratectomy (PRK) with mitomycin-C (MMC) 0.02% in patients with moderate myopia. METHODS In this prospective interventional case series, patients with moderate myopia (spherical equivalent refractive error from -4.0 to -8.0 D) underwent PRK with a single intraoperative appli...

The aim of this study was to determine the change in the degree of astigmatism in patients treated with customized ablation photorefractive keratectomy (PRK). This is a cross-sectional study that involved 92 otherwise healthy subjects with regular and irregular astigmatism ≥ 1.25 D (mean age: 39.09 ± 7.72 years; range: 20-59 years). All study subjects were treated with customized ablation PRK u...

PURPOSE To study the long-term results of photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) in low to moderate myopic corrections using the Pulzar Z1 system (CustomVis), a 213 nm wavelength solid-state laser. SETTING University refractive surgery center. METHODS This prospective noncomparative case series comprised 20 patients (40 eyes) who had refractive surgery us...

PURPOSE To determine the measurement reliability of CorVis ST, a dynamic Scheimpflug analyser, in virgin and post-photorefractive keratectomy (PRK) eyes and compare the results between these two groups. METHODS Forty virgin eyes and 42 post-PRK eyes underwent CorVis ST measurements performed by two technicians. Repeatability was evaluated by comparing three consecutive measurements by technic...

PURPOSE To comparatively investigate the clinical outcomes, vector parameters, and corneal aberrations of small incision lenticule extraction (SMILE) with a triple centration technique and corneal wavefront-guided transepithelial photorefractive keratectomy (PRK) for the correction of high astigmatism. METHODS This retrospective, comparative case series study included 89 eyes (89 patients) th...

Purpose To determine whether topical Substance-P (SP) plus insulin-like growth factor-1 (IGF-1) can improve corneal healing after photorefractive surface ablation in a rabbit. Methods After a 9.0-mm corneal de-epithelialization using a combination of chemical (18% alcohol) and mechanical debridement, excimer photorefractive surface ablation was performed bilaterally in eight rabbits (16 eyes)...

PURPOSE To study the corneal epithelial and stromal thickness profile changes after photorefractive keratectomy (PRK) for myopia. METHODS Retrospective analysis of the postoperative corneal epithelial and stromal thickness profile changes in 46 left eyes of 46 patients treated with PRK for myopia. Corneal and epithelial thickness maps within the central 6 mm were obtained by anterior segment ...

PURPOSE To evaluate a series of patients with corneal ectasia after LASIK that underwent the Athens Protocol: combined topography-guided photorefractive keratectomy (PRK) to reduce or eliminate induced myopia and astigmatism followed by sequential, same-day ultraviolet A (UVA) corneal collagen cross-linking (CXL). METHODS Thirty-two consecutive corneal ectasia cases underwent transepithelial ...

PURPOSE To investigate the effect of nepafenac 0.3% in a once daily dosage regarding pain and healing after photorefractive keratectomy (PRK). METHODS This was a prospective, comparative, contralateral randomized study of 35 patients undergoing PRK for the correction of low to moderate myopia and myopic astigmatism. After randomization, patients received nepafenac 0.3% ophthalmic suspension o...