Variegate porphyria (VP) is an autosomal dominant disease caused by mutations of the protoporphyrinogen oxidase (PPOX) gene. This porphyria has unique characteristics which can induce acute neurovisceral attacks and cutaneous lesions that may occur separately or together. We herin report a 58-years-old VP patient complicated with cholelithiasis. A sequencing analysis indicated a novel c.40G>C m...

Bloom syndrome is an extremely rare inherited disorder. We present a case of Bloom syndrome with a chromosomal study in a Mexican five-year-old patient who presented growth retardation, narrow facies with poikiloderma, café-au-lait, macules and photosensitivity.

A polydopamine (PDA) thin film with a dense and conformal surface was prepared under optimized deposition conditions using O2 gas as an oxygen source. The PDA-based organic phototransistors exhibited high photosensitivity and photo-controlled switching properties under light illumination.

Bloom syndrome is a rare autosomal recessive genetic disorder, which is characterized by telangiectasia and erythema in the butterfly area of the face, dwarfism and photosensitivity. The case presented herein is a 22-year-old man who referred with facial erythema and telangiectasia (Resembling lupus erythematosus). The skin lesions were exacerbating during summer. Other clinical findings were p...

Various hepatogenous photosensitivity diseases of ruminants in South Africa, caused by plants, fungi and an alga, are described. Information is given on botanical, mycological, toxicological, clinical and pathological aspects of the diseases. The intoxications were grouped according to the primary site of involvement and type of lesions in the liver. The aetiology, pathogenesis, and diagnosis o...

Photosensitive disorders in children are not uncommon in our country. It is often difficult to establish the diagnosis, either due to confusing presentation or ignorance by the parents. We review the presentation and management of photosensitive disorders in children.Detailed history and thorough clinical examination is essential in arriving at a particular diagnosis. Photosensitive disorders i...

Intrinsically photosensitive retinal ganglion cells (ipRGCs) mediate numerous nonvisual phenomena, including entrainment of the circadian clock to light-dark cycles, pupillary light responsiveness, and light-regulated hormone release. We have applied multielectrode array recording to characterize murine ipRGCs. We find that all ipRGC photosensitivity is melanopsin dependent. At least three popu...

Photosensitivity disorders in children include a wide array of conditions, many of which are unique to this age group. Prompt diagnosis of these disorders becomes difficult at times because of the overlapping clinical pictures. Genodermatoses and metabolic disorders may have associated systemic involvement, which may lead to these children presenting to pediatricians who may overlook the photos...

A 7-year-old boy presented with numerous asymptomatic whitish flat lesions of varying sizes over the whole body for last two years. Patient was diagnosed as kala-azar about 3 years previously, and was treated suboptimally. There was no other systemic complaints like fever, pain abdomen or photosensitivity. On examination, there were asymptomatic hypopigmented macules and patches over the face (...