Various glycoprotein conjugate vaccines have been developed for the prevention of invasive meningococcal disease, having significant advantages over pure polysaccharide vaccines. One of the most important features of the conjugate vaccines is the induction of a T-cell dependent immune response, which enables both the induction of immune memory and a booster response after repeated immunization....

The aim of this study was to determine the chemical composition physico-chemical properties, fatty acid and tocopherol compositions and total phenolic compounds and evaluate the radical-scavenging activity of crude oil extracted from passion fruit (Passiflora edulis f. flavicarpa) seeds, aiming to use the agro-industrial by-products. The oil seed extraction was performed by Soxhlet method and t...

Many biological activities originate from interactions between small-molecule ligands and their protein targets. A detailed structural and physico-chemical characterization of these interactions could significantly deepen our understanding of protein function and facilitate drug design. Here, we present a large-scale study on a non-redundant set of about 20,000 known ligand-binding sites, or po...

The study was conducted to study the effect of age viz., young (6-9 months) and adult (2 years) on physico-chemical characteristics, proximate composition, amino acid, fatty acid and cholesterol content of Kodiadu goat meat. The Longissimus dorsi muscle was collected from these animals and the physico-chemical characteristics viz., pH, water holding capacity, instrumental colour, muscle fi bre ...

Runoff waters from a main bridge near Nantes (France), surface waters and pore waters in the infiltration basin collecting runoff were analysed after filtration and ultrafiltration to investigate the role of colloids in the transfer of trace metals (Zn, Cu and Pb) from the road to the groundwater. The role of the basin in mitigation of the variations of physico-chemical parameters and chemical ...

Objective of this study was to investigate the effect of short term frozen storage of milk and curd on textural properties and physico-chemical composition of white brined goat cheese. Raw milk and curds (at various stages of pressing) were frozen and kept for seven days at -27 °C. Following the freezing, all the experimental cheeses were manufactured by the standard procedure, the same that wa...

Sir: Protein geranylgeranylation of small GTP-binding proteins, such as Rho, Rac, Cdc42 and Rab1), is essential for the function of the modified proteins. Protein geranylgeranylation is a key target for chemotherapeutic intervention in a number of diseases. Because geranylgeranyl diphosphate synthase (GGPP synthase)2,3) is involved in a pathway for protein geranylgeranylation, we screened an in...

In the present study, water samples from 3 stations of Kor river, Iran were analyzed for seasonal fluctuation of physico-chemical parameters, i.e. air and water temperature, dissolved oxygen, BOD, COD, total nitrogen, total hardness, pH, alkalinity, acidity, total dissolved solid and water current. Effect of physico-chemical parameters on surface water density of rotifers was also studied. Duri...

Polyesteramide resin (MAPEAM) was prepared from N,N-bis(2-hydroxy ethyl) Melia azedarach oil fatty amide (HEMAFA) a precursor of natural renewable resource using polycondensation reaction with maleic acid. With the view to improve the physico-mechenical properties aluminium was incorporated in backbone of the polymer to obtain the alumina incorporated polyesteramide resin of Melia azedarach see...

the design and manufacture of direct smelting reactors depends on the rate of the physico-chemical reactions that occur in the particles immersed into the molten bath. investigation of the effects of the important parameters that influence the smelting rate of the particles that in the furnace are both difficult and expensive if the aimed is to take measure meuts under real practical conditions...