نتایج جستجو برای: pit

تعداد نتایج: 8837  

Journal: :The Journal of clinical investigation 2011
Masaaki Yamamoto Genzo Iguchi Ryoko Takeno Yasuhiko Okimura Toshiaki Sano Michiko Takahashi Hitoshi Nishizawa Anastasia Evi Handayaningshi Hidenori Fukuoka Maya Tobita Takatoshi Saitoh Katsuyoshi Tojo Atsuko Mokubo Akio Morinobu Keiji Iida Hidesuke Kaji Susumu Seino Kazuo Chihara Yutaka Takahashi

The pituitary-specific transcriptional factor-1 (PIT-1, also known as POU1F1), is an essential factor for multiple hormone-secreting cell types. A genetic defect in the PIT-1 gene results in congenital growth hormone (GH), prolactin (PRL), and thyroid-stimulating hormone (TSH) deficiency. Here, we investigated 3 cases of adult-onset combined GH, PRL, and TSH deficiencies and found that the endo...

Journal: :Journal of leukocyte biology 2005
Neal R Barshes Samuel Wyllie John A Goss

Recent advances in clinical protocols have improved the outcomes of pancreatic islet transplantation (PIT), yet PIT recipients typically require pancreatic islet grafts derived from multiple donors to achieve insulin independence. This along with experimental models of syngeneic PIT, showing that up to 60% of pancreatic islet tissue undergoes apoptosis within the first several days post-transpl...

Journal: :Hong Kong medical journal = Xianggang yi xue za zhi 2012
H T Fung W H Yung Paul Crow K K Lam Kenny K W Ho K S Tan S K Lam Y Ke Alessandro Grioni O F Wong Gary Ades C W Kam M L Tse

OBJECTIVE To compare the relative efficacy of the green pit viper antivenom from Thailand and Agkistrodon halys antivenom from China. DESIGN. In-vivo experimental study. SETTING A wildlife conservation organisation, a university, a poison information centre, and a regional hospital in Hong Kong. MAIN OUTCOME MEASURES Pre- and post-antivenom lethal dose 50 (LD50) of the Cryptelytrops albolab...

2013
Damian Tworek Malgorzata Bochenska-Marciniak Izabela Kuprys-Lipinska Maciej Kupczyk Piotr Kuna

BACKGROUND Two different regimens of subcutaneous immunotherapy (IT), perennial or preseasonal, may be used in the treatment of seasonal allergy. The aim of this study was to compare the efficacy and safety of perennial IT (PIT) and preseasonal IT (PSIT) in patients suffering from seasonal rhinoconjunctivitis. METHODS The study was planned as a randomized, double-blind, comparative study on t...

2004
LLOYD W. MORRISON

Antlion larvae that construct conical pits to capture prey may strongly affect foraging of ants and other arthropods, yet are usually abundant only in sheltered microhabitats. Larval antlion (Myrmeleon crudelisWalker) densities increased in exposed areas in central Texas in late summer and early autumnof 1998, presumably because of extended dry conditions. I conducted a study to quantify larval...

Journal: :Addiction biology 2016
Maria Garbusow Daniel J Schad Miriam Sebold Eva Friedel Nadine Bernhardt Stefan P Koch Bruno Steinacher Norbert Kathmann Dirk E M Geurts Christian Sommer Dirk K Müller Stephan Nebe Sören Paul Hans-Ulrich Wittchen Ulrich S Zimmermann Henrik Walter Michael N Smolka Philipp Sterzer Michael A Rapp Quentin J M Huys Florian Schlagenhauf Andreas Heinz

In detoxified alcohol-dependent patients, alcohol-related stimuli can promote relapse. However, to date, the mechanisms by which contextual stimuli promote relapse have not been elucidated in detail. One hypothesis is that such contextual stimuli directly stimulate the motivation to drink via associated brain regions like the ventral striatum and thus promote alcohol seeking, intake and relapse...

2010
A. D. Akbari M. Osanloo M. A. Shirazi

Planning and design procedure of an open pit mining project just can be started after ultimate pit determination. In the carried out study in this paper it was shown that the most important factor in ultimate pit determination and in consequence in the whole planning and design procedure of an open pit mine is the metal price. Metal price fluctuations in recent years were exaggerated and impose...

Journal: :The New phytologist 2011
Steven Jansen Emmanuelle Gortan Frederic Lens Maria Assunta Lo Gullo Sebastiano Salleo Alexander Scholz Anke Stein Patrizia Trifilò Andrea Nardini

• The hydraulic conductance of angiosperm xylem has been suggested to vary with changes in sap solute concentrations because of intervessel pit properties. • The magnitude of the 'ionic effect' was linked with vessel and pit dimensions in 20 angiosperm species covering 13 families including six Lauraceae species. • A positive correlation was found between ionic effect and vessel grouping parame...

2013
Kiho Im Jong-Min Lee Seun Jeon Jong-Heon Kim Sang Won Seo Duk L. Na P. Ellen Grant

Sulcal pit analysis has been providing novel insights into brain function and development. The purpose of this study was to evaluate the reliability of sulcal pit extraction with respect to the effects of scan session, scanner, and surface extraction tool. Five subjects were scanned 4 times at 3 MRI centers and other 5 subjects were scanned 3 times at 2 MRI centers, including 1 test-retest sess...

Journal: :The Journal of pharmacology and experimental therapeutics 1998
B F King S S Wildman A Townsend-Nicholson G Burnstock

Follicular Xenopus oocytes possess a novel receptor where both adenosine and ATP activate a cAMP-dependent, nonrectifying K+-current. Five compounds, alpha,beta-methylene ATP (alpha, beta-meATP), 8-(p-sulfophenyl)theophylline (8-SPT), theophylline, 2, 2'-pyridylisatogen tosylate (PIT) and suramin, were tested as antagonists of adenosine- and ATP-activated K+-currents. The descending order of ac...

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