The purpose of this article is to provide an overview of the PKI project initiated part of the UAE national ID card program. It primarily shows the operational model of the PKI implementation that is indented to integrate the federal government identity management infrastructure with e-government initiatives owners in the country. It also explicates the agreed structure of the major components ...

BACKGROUND cAMP-dependent protein kinase (PKA) has been implicated in the asexual stage of the Toxoplasma gondii life cycle through assaying the effect of a PKA-specific inhibitor on its growth rate. Since inhibition of the host cell PKA cannot be ruled out, a more precise evaluation of the role of PKA, as well as characterization of the kinase itself, is necessary. METHODOLOGY/PRINCIPAL FIND...

The present study was undertaken in order to identify the inhibitory site of the heat-stable inhibitor of cAMP-dependent protein kinase (PKI) and to synthesize a peptide that could serve as a useful inhibitor of the enzyme. Digestion of purified PKI by mast cell proteinase II yielded a peptide fragment that retained inhibitory activity. A sequence of 20 amino acids of the peptide, (sequence in ...

It has been conventional wisdom that, for e-commerce to fulfil its potential, each party to a transaction must be confident about the identity of the others. Digital signature technology, based on public key cryptography, has been claimed as the appropriate means of achieving this aim. Digital signatures do little, however, unless a substantial ’public key infrastructure’ (PKI) is in place to p...

The catalytic subunit of PKA (PKAc) exhibits three major conformational states (open, intermediate, and closed) during the biocatalysis process. Both ATP and substrate/inhibitor can effectively induce the conformational changes of PKAc from open to closed states. Aiming to explore the mechanism of this allosteric regulation, we developed a coarse-grained model and analyzed the dynamics of confo...

Under modern high-tech conditions, the importance of personnel authorization security is increasingly prominent. A set safe method can ensure that human resources are properly distributed to each unit, thus providing reliable guarantee for successful completion tasks. However, current still paper-based or verbal, prone errors inconsistencies, and difficult verify. In this paper, a digital Tiger...

Conventionally, public key certificates bind one subject with static so that the can facilitate services of infrastructure (PKI). In PKI, need to be renewed (or revoked) for several practical reasons, including certificate expiration, private breaches, condition changes, and possible risk reduction. The renewal process is very costly, especially those environments where online authorities are n...

Recently, vehicular ad-hoc network (VANET) has emerged as an excellent candidate to change the life style of the traveling passengers along the roads and highways in terms of improving the safety levels and providing a wide range of comfort applications. Due to the foreseen impact of VANETs on our lives, extensive attentions in industry and academia are directed towards bringing VANETs into rea...

Previously, we reported that cAMP/PKA signaling is involved in GPER-mediated coronary relaxation by activating MLCP via inhibition of RhoA pathway. In the current study, we tested the hypothesis that activation of GPER induces coronary artery relaxation via inhibition of RhoA/Rho kinase pathway by cAMP downstream targets, exchange proteins directly activated by cAMP (Epac) as well as PKA. Our r...