A 66-year-old patient with polyarteritis nodosa presented with thrombocytosis and was found to have circulating immune complexes. Treatment by plasma exchange produced symptomatic improvement and lowered both the platelet count and the level of immune complexes. While plasma exchange is a useful technique in investigating the pathogenesis of the disease, predisolone is a more convenient way of ...

In a previous paper (1), the synthesis and entry into the plasma of the protein moiety of the different lipoprotein classes has been described. The present studies deal with the metabolism of the free and esterified cholesterol of the lipoproteins. Relatively little is known of the metabolism of the plasma lipids as they exist in the various lipoprotein fractions. Study of certain lipids is dif...