performance liquid chromatography (HPLC) could represent an important approach in basic platelet research or in clinical diagnosis of platelet function disorders [8]. However, implementation of such methods (TEM and HPLC) in a routine laboratory for clinical hemostaseology or blood banks could be challenging. A novel platelet activation test in unprocessed blood (pac-tUB) based on flow cytometr...

OBJECTIVES: The purpose of this study was to analyze the impact COVID-19 on use blood components in an oncology hospital. MATERIAL AND METHODS: Retrospective cross-sectional quantitative nature cohort, with comparative analysis component requests by hospital city Juiz de Fora, Minas Gerais, Brazil, 2019 and 2020. RESULTS: There a reduction 14.36% for at service 2020 (p-value = 0,002), 27.33% pl...

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In trauma patients, resuscitation treatment of intravascular volume may cause haemodilution including blood cell- and plasma-dilution. After plasma-dilution, fibrinogen is the first factor that decreases to critically low concentrations. Fibrin formed in lowered levels is susceptible to fibrinolysis, a natural forerunner for bleeding. To assess whether a fibrinogen concentrate or a factor XIII ...