INTRODUCTION: Activated platelets are known to release many kinds of growth factors such as Platelet Derived Growth Factor (PDGF) and Transforming Growth Factor-β (TGF-β). Platelet-rich plasma (PRP) is a fraction of plasma in which platelets are concentrated and is reported to be utilized as a source of multiple growth factors that promote tissue repair. Recent studies has shown that platelet r...

BACKGROUND Platelet-rich plasma (PRP) has been advocated as one treatment for cartilage tissue regeneration. To date, several different platelet-rich formulations have been available, but a deep knowledge of their composition and mechanism of action in a specific clinical use is needed. The aim of this study was to investigate the effect of various PRP formulations on human chondrocytes in vitr...

Background Steroid injection is a widespread treatment for plantar fasciitis but seems to be useful lesser extent, Platelet-rich Plasma (PRP) injections into the fascia start healing process required stop degeneration of at its root.Aim study To compare analgesic efficacy, functional outcome, degree satisfaction and improvement fascial thickness echogenicity after platelet-rich plasma versus co...

background: platelet preparations have been used for a wide variety of clinical applications such as hemorrhage, tissue engineering and cellular therapy. platelet concentrates can be prepared by the apheresis method or from the whole blood using the buffy-coat or platelet-rich plasma methods. the purpose of this study was to compare four variations of platelet-rich plasma method based on double...

Abstract Platelet derivatives are commonly used in wound healing and tissue regeneration. Different procedures of platelet preparation may differentially affect growth factor release and cell growth. Preparation of platelet-rich fibrin (PRF) is accompanied by release of growth factors, including platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and transforming gr...

Context: Diabetic foot ulcer (DFU) remains a devastating and prevalent complication of diabetes, which leads to significant morbidity, mortality, economic implications. Outcomes DFU management are still unsatisfactory, warranting innovations improve them. One accessible promising potential for treating is autologous platelet-rich plasma (PRP), blood product abundant in bioactive molecules. Plat...

Platelet-rich plasma (PRP) commonly refers to blood products which contain a higher platelet (PLT) concentration as compared to normal plasma. Autologous PRP has been shown to be safe and effective in promoting the natural processes of soft tissue healing or reconstruction in humans and horses. Variability in PLT concentration has been observed in practice between PRP preparations from differen...

Psoriatic arthritis has been known to cause many inflammatory clinical features, including synovitis. In the past, synovitis primarily treated with NSAIDs, corticosteroid injections, and synovectomy when needed. This report outlines a 49-year-old female caused by psoriatic who did not respond conventional treatment options was apprehensive surgery. She offered platelet rich plasma (PRP) injecti...

  Objective(s): Platelet-rich plasma (PRP) has recently emerged as a promising strategy in regenerative medicine due to its multiple endogenous growth factors. Little is known about the role of PRP as a promoter in chondrogenesis of human adipose derived stem cells (hADSCs). The aim of this study was to determine whether PRP may be considered as a natural and easy achievable source o...

the purpose of the present randomized clinical trial study was to compare the effectiveness of bovine porous bone mineral (bpbm) with and without plasma rich in growth factors (prgf) in the treatment of mandibular class ii furcation defects.in seven patients, nine pairs of symmetric buccal or lingual mandibular class ii furcation defects were treated. in each patient, one defect received bpbm (...