Post-marketing safety studies are an important tool for understanding and monitoring the safety profiles of drugs in the clinical setting. Their importance has attracted not only the attention of regulators for reinforcing legislation but also led to recent changes in European Union (EU) regulations; these regulations have influenced the practice of Post-Authorization Safety Study (PASS) by mar...

Cloud computing environments have introduced a new model of computing by shifting the location of computing infrastructure to the Internet network to reduce the cost associated with the management of hardware and software resources. The Cloud model uses virtualization technology to effectively consolidate virtual machines (VMs) into physical machines (PMs) to improve the utilization of PMs. Stu...

The importance of continuous improvement has brought performance measurement system (PMS) into attention. Although widely discussed, PMS often plays a passive role in verifying the effectiveness of critical decisions associated with a manufacturing system. The web-based manufacturing environment provides real-time data collection and cross-platform communication, which enhances the ability of a...

Serum levels of progesterone, total testosterone, free testosterone, androstenedione (A2), dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulphate (DHEAS), 17-OH-progesterone (17-OHP), and sex hormone binding globulin (SHBG) were measured in the follicular phase, around ovulation, and in the luteal phase of 11 women with severe premenstrual irritability and dysphoria and in 11 age-matche...

The aim of the work is the need of post marketing surveillance in India. The objective in Postmarketing surveillance is to estimate the strength of the association between adverse events (AEs) and drug exposures that vary over time. In premarketing testing, the numbers and types of patients used to demonstrate a drug’s efficacy and safety are limited compared with the numbers and types of patie...

In this paper, we present a novel multi-objective ant colony system algorithm for virtual machine (VM) consolidation in cloud data centers. The proposed algorithm builds VM migration plans, which are then used to minimize over-provisioning of physical machines (PMs) by consolidating VMs on under-utilized PMs. It optimizes two objectives that are ordered by their importance. The first and foremo...

This study presents the nutrient data collected from women who were being screened for premenstrual syndrome (PMS) for entry into an intervention study. Screening was by the Steiner self-rated questionnaire. One hundred and forty-four overweight women completed the screening process and eighty-eight met the criteria for PMS. All women kept 4 d diet diaries pre- and postmenstrually over two mens...

The purpose of this study was to investigate the influence of personality on Premenstrual Syndrome (PMS) in athletes. The sample included 25 Brazilian athletes, between 18 and 49 years of age. A diary of PMS symptoms was used (based on the criteria from the American College of Obstetricians and Gynecologist, ACOG, 2000) and the Factorial Personality Inventory (Pasquali, Azevedo, & Ghesti, 1997)...

Potassium methyl siliconate (PMS) was investigated as a new nano modifier of wood fiber and wood flour to improve the compatibility between the fiber/flour and the plastic matrix in fiber reinforced plastic composites. Before injection molding, bleached and brown pulp fibers and mixed species wood flour were pretreated in PMS solutions. The morphology of the treated and untreated fiber and flou...

Oral administration is the most commonly used and readily accepted form of drug delivery; however, it is find that many drugs are difficult to attain enough bioavailability when administered via this route. Polymeric micelles (PMs) can overcome some limitations of the oral delivery acting as carriers able to enhance drug absorption, by providing (1) protection of the loaded drug from the harsh ...