Pneumocystis jiroveci is an important agent of pneumonia in immunocompromised hosts. Usually, this pathogen is detected by Giemsa or direct fluorescence stains of bronchoalveolar lavage (BAL) fluids. Microscopic methods, however, have 2 disadvantages. P. jiroveci is not stable outside the human body, which means that slow sample transport might result in false-negative results. Additionally, ex...

Pneumocystis pneumonia is considered one of the most serious fungal respiratory infections in immunocompromised patients and animals. Molecular comparisons of various gene sequences clearly demonstrated that the single name P. carinii corresponds in fact to a complex group of eukaryotic organisms, which should be assigned to the kingdom Fungi (Edman et al., 1988; Stringer, 1996; AliouatDenis et...

BACKGROUND In patients with chronic respiratory disease, Pneumocystis jirovecii (P. jirovecii) colonization is observed, and may influence disease progression and systemic inflammation. Pneumocystis pneumonia causes interstitial changes, so making a diagnosis of PCP in patients who have interstitial pneumonia (IP) with P. jirovecii colonization is sometimes difficult based on radiography. MET...

Once regarded as an AIDS-defining illness, Pneumocystis pneumonia (PcP) is nowadays prevailing in immunocompromised HIV-negative individuals such as patients receiving immunosuppressive therapies or affected by primary immunodeficiency. Moreover, Pneumocystis clinical spectrum is broadening to non-severely-immunocompromised subjects who could be colonized by the fungus while remaining asymptoma...

BACKGROUND Pulmonary infections caused by Pneumocystis jirovecii in immunocompromised host can be associated with cysts, pneumatoceles and air leaks that can progress to pneumomediastinum and pneumothoraxes. In such cases, it can be challenging to maintain adequate gas exchange by conventional mechanical ventilation and at the same time prevent further ventilator-induced lung injury. We report ...

Between January 2002 and July 2003, 173 bronchoalveolar lavage (BAL) specimens from 150 patients (19 HIV-infected and 131 non-HIV-infected patients) were evaluated for identification of Pneumocystis jiroveci (formerly known as Pneumocystis carinii f. sp. hominis) using staining techniques, conventional PCR (mtLSUrRNA gene) and real-time PCR (MSG gene). Test results were compared to Pneumocystis...

Various non-invasive investigations were carried out in patients infected with HIV who had respiratory symptoms with and without pneumocystis pneumonia (with pneumonia, n = 13 (five smokers); without pneumonia, n = 22 (13 smokers]. These included chest radiography; lung function tests (forced expiratory volume in one second, forced vital capacity; transfer factor and coefficient for carbon mono...

Bakteriyel ve fungal infeksiyonlar COVID-19 ile birlikte görülebilir. Ayrıca, bazı infeksiyon hastalıkları infeksiyonuna bağlı pnömoni karışabilir. Bu yazıda, pnömonisi ön tanısıyla kliniğimize sevkedilen, HIV Pneumocystis jiroveci akciğer tüberkülozu tanısı konulan 60 yaşında bir erkek hasta sunuldu. Hastanın başvuru esnasındaki ateş, öksürük balgam çıkarma yakınmaları tedavisi sonrasında tama...

conclusions in molecular epidemiology studies, nested pcr has higher sensitivity than pcr. results of this study support the colonization of p. jiroveci in patients receiving lung transplantation. patients who are carriers of p. jiroveci are at a higher risk of p. jiroveci pneumonia. results the genome of p. jiroveci was revealed by a 346 bp pcr product in the initial amplification and a 120 bp...