Poisoning is the last consequence of drug action that harmful to body. It may be due overdose or prolonged use a drug. Any substance causes deleterious, unwanted and effects on body called poison. can acute chronic. Short time exposure poison poisoning whereas repeated, long term continuous chronic poisoning. In poisoning, symptoms not seen after each period. Poison cause when they are orally t...

BACKGROUND This report is the 25th Annual Report of the American Association of Poison Control Centers (AAPCC; http://www.aapcc.org) National Poison Data System (NPDS). During 2007, 60 of the nation's 61 U.S. Poison Centers upload case data automatically. The median upload time is 14 [5.3, 55] (median [25%, 75%]) min creating a real-time national exposure database and surveillance system. MET...

UNLABELLED A retrospective case review study of viper envenomations collected by the Marseille's Poison Centre between 1996 and 2008 was performed. RESULTS 174 cases were studied (52 grade 1 = G1, 90 G2 and 32 G3). G1 patients received symptomatic treatments (average hospital stay 0.96 day). One hundred and six (106) of the G2/G3 patients were treated with the antivenom Viperfav* (2.1+/-0.9 d...

INTRODUCTION Tolperisone is a centrally acting muscle relaxant that acts by blocking voltage-gated sodium and calcium channels. There is a lack of information on the clinical features of tolperisone poisoning in the literature. The aim of this study was to investigate the demographics, circumstances and clinical features of acute overdoses with tolperisone. METHODS An observational study of a...

chlorinated biphenyl (PC8I mixtures had been described previously. High mortality, liver damage, and edema were associated with only two of the three PCB5. Using column and gas chromatography, several compounds were identified in the diethylether fracdon of these two PCBs. A chick embryo assay confirmed the high toxicity of this fraction. Mass spectremetric and microcoulometric analyses indicat...