a new approach for pole placement of nonlinear systems using state feedback and fuzzy system is proposed. we use a new online fuzzy training method to identify and to obtain a fuzzy model for the unknown nonlinear system using only the system input and output. then, we linearized this identified model at each sampling time to have an approximate linear time varying system. in order to stabilize...

The ability of the Schizosacchromyces pombe spindle pole body to nucleate microtubules is activated at the onset of mitosis for forming a mitotic spindle, but it is inactivated during interphase. We have previously developed an in vitro assay for studying the molecular mechanism of spindle pole body activation using permeabilized interphase S. pombe cells and Xenopus mitotic extracts. We have s...

PURPOSE The aim of this study was to confirm the prognostic significance of POLE exonuclease domain mutations (EDM) in endometrial carcinoma patients. In addition, the effect of treatment on POLE-mutated tumors was assessed. EXPERIMENTAL DESIGN A retrospective patient cohort of 496 endometrial carcinoma patients was identified for targeted sequencing of the POLE exonuclease domain, yielding 4...

How cells establish and dynamically change polarity are general questions in cell biology. Cells of the rod-shaped bacterium Myxococcus xanthus move on surfaces with defined leading and lagging cell poles. Occasionally, cells undergo reversals, which correspond to an inversion of the leading-lagging pole polarity axis. Reversals are induced by the Frz chemosensory system and depend on relocaliz...

Studies of the temporal pole (TP) in schizophrenia patients are not consistent. The aim of this study was to investigate morphometric anomalies of the TP in first-episode schizophrenia patients. Patients did not significantly differ from controls in the TP morphometric variables evaluated. Clinical variables were not significantly related to the TP.

Brain-based evidence has implicated the frontal pole of the brain as important for analogical mapping. Separately, cognitive research has identified semantic distance as a key determinant of the creativity of analogical mapping (i.e., more distant analogies are generally more creative). Here, we used functional magnetic resonance imaging to assess brain activity during an analogy generation tas...

The switched reluctance motor is a simple and robust machine, which has found application over a wide power and speed ranges in different shapes and geometries. This paper introduces a new configuration for a two phase unidirectional switched reluctance motor/field assisted generator. The proposed novel motor/generator consists of two magnetically independent stator and rotor sets (layers), whe...

In this paper, we present a mathematical model for determining the optimal radius of the iron pole shape in spoke-type permanent-magnet (PM) machines (STPMM) in order to minimize the pulsating torque components. The proposed method is based on the formal resolution of the Laplace’s and Poisson’s equations in a Cartesian pseudo-coordinate system with respect to the relative permeability effect o...

Segmental pattern in the Drosophila embryo is established by two maternal factors localized to the anterior and posterior poles of the egg cell. Here we provide molecular evidence that the localized posterior factor is the RNA of the nanos (nos) gene. nos RNA is localized to the posterior pole of early embryos, and nos protein acts at a distance to direct abdomen formation. Synthetic nos RNA ha...