Considering lifecycle cost analysis during the design phase of thermal systems gives the design effort more worth. Furthermore thermodynamic exergetic optimization is a proven useful method for determining the most lifecycle cost optimal design of thermal systems for given thermodynamic constraints. The most thermodynamic efficient heat exchanger design basing on first law analysis may not be t...

The Na(+)/Ca(2+) exchanger is the major Ca(2+) extrusion mechanism in cardiac myocytes. The activity of the cardiac Na(+)/Ca(2+) exchanger is dynamically regulated by intracellular Ca(2+). Previous studies indicate that Ca(2+) binding to a high-affinity Ca(2+)-binding domain (CBD1) in the large intracellular loop is involved in regulation. We generated transgenic zebrafish with cardiac-specific...

We previously showed that acute arterial hypertension induces an inhibition of fluid and NaCl reabsorption in proximal tubules of Sprague-Dawley rats, which is associated with a rapid reversible internalization of apical Na(+)/H(+) exchanger in brush border. To determine whether there is a corresponding inhibition of apical Na(+)/H(+) exchanger activity in proximal tubules to account for the re...

The state-of-the-art latent heat energy storage system is equipped with aluminum fins at the heat exchanger pipes in order to compensate the low thermal conductivity of the phase change material (PCM). The necessary amount of fins is directly coupled to the capacity of the storage system, what makes larger systems expensive. The PCMflux concept is developed in order to realize both a controllab...

Evidence for an important role for Na(+)/H(+) exchangers in diabetic complications is emerging. The aim of this study was to evaluate whether Na(+)/H(+) exchanger 1 inhibition reverses experimental peripheral diabetic neuropathy. Control and streptozotocin-diabetic rats were treated with the specific Na(+)/H(+) exchanger 1 inhibitor cariporide for 4 wk after 12 wk without treatment. Neuropathy ...

Leakage in heat exchanger tubes can result in unreliable products and dangerous situations, which could cause great economic losses. Along with fast development of modern acoustic detection technology, using acoustic signals to detect leakage in heat exchange tube has been gradually accepted and considered with great potential by both industrial and research societies. In order to further advan...

Recently, there have been many studies on dehumidifiers with a low flow rate of liquid desiccant, in which a plate-type heat exchanger with internal cooling is adopted. If the low flow rate of a liquid desiccant maintains a thin liquid film on the heat exchanger surface, heat and mass transfer performance would improve, the stability of the liquid film would increase, and there would be no entr...

The Na(+)-H+ exchanger has important modulatory effects on vascular smooth muscle cell proliferation and contractility. Increased Na(+)-H+ exchange activity is a general property of many tissues, including mesenteric artery and cultured vascular smooth muscle cells, in the spontaneously hypertensive rat (SHR). In the present work, we investigated whether alterations in the steady-state levels o...

This paper presents how the thermal performance of an existing finned-tube heat exchanger is determined experimentally. In the experiment, heat is transferred from an exhaust gas stream to a thermal oil. The experimental setup is discussed including the thermal fluid selection process, the components, instrumentation and resultant measurement uncertainty. The heat transfer is calculated individ...