Acetyl-coenzyme A carboxylase α (ACC-alpha) is considered as the key regulatory enzyme in fatty acid biosynthesis. ACC-alpha gene is located on Caprine chromosome 11 and is polymorphic in many goat breeds. In the current study, we aimed to find possible single nucleotide polymorphisms (SNPs) in the exon 1 region of the ACC-alpha gene in Iranian Mahabadi goat breed. Genomic DNA was extracted fro...

the ataxia telangiectasia mutated gene (atm), candidate for breast cancer susceptibility gene, encode a 350-kda protein belongs to the core components of dna-damage response machinery. female at carriers have at least 5-fold increase risk for breast cancer. reduction in atm expression is shown in multiple studies in breast tissues. we aimed to perform a research to measure the atm mrna expressi...

background and aims: the causal agents of viral lettuce big vein disease are two viruse, lettuce big vein associated virus (varicosavirus) and mirafiori lettuce virus (ophiovirus). these viruses have coat proteins of similar size but have different morphologies and serologically unrelated.the purpose of this study was to distinguish and detect lbvav and milv in lettuce fields in tehran province...

background: one of the most common sexual‑transmitted infections among women is human papillomavirus (hpv) infection which is associated with genital cancers. different studies in iran reported various prevalences, and combining their results could be important for health policy makers. this study aims to determine the total prevalence of hpv infection as well as its related genotypes, particul...

conclusions there is a significant correlation between tympanosclerosis and h. pylori (p = 0.002). this correlation can single out h. pylori as a pathological factor in the development of tympanosclerosis; however, further studies are needed to prove this correlation. results from a total of 19 patients with tympanosclerosis , 16 cases (84.2%) were h. pylori positive, while in the control group...

objective: the aim of this study was to investigate the existence of human t-lymphotropic virus type 1 (htlv-1) in subgingival plaque of htlv-1 seropositive pa-tients. materials and methods: a total of 18 patients including 13 females and fivemales, with a mean age of 37 years participated in this descriptive study. half of them were htlv-1 carriers and the others were in htlv-1 associated myel...

background while tuberculosis (tb) can be diagnosed by microscopy and culture, the sensitivity of ziehl-neelsen staining is variable and culture results require 4 - 8 weeks to be determined. polymerase chain reaction (pcr) and its modifications, including nested pcr, might be promising methods for the rapid diagnosis of tb. objectives this study aimed to evaluate the performance of nested pcr o...

conclusions the results of this study phenotypically and genotypically confirmed the high frequency of esbl-producing strains, such as the ctx-m and ctx-m-1 genes, among enterobacteriaceae isolates in our region. therefore, use of antibiotic susceptibility testing for the detection of esbl isolates prior to the prescription of beta-lactam antibiotics is recommended. this could help prevent the ...

backgoround: plant diseases, caused by a wide range of phytopathogenic fungi, could be managed using of trichoderma sp, as a biocontrol agent. cell wall degrading enzymes like chitinase from t. harzianum are important means for fungal pathogen inhibition. overexpression of these chitinase enzymes can improve the antagonistic potential of trichoderma sp. strains. objectives: this study aimed to ...