the main objective of present research work is to formulate the clopidogrel fast dissolving tablets. clopidogrel, an antiplatelet drug, belongs to bcs class-ii and used to control heart attack, hypertension by inhibiting platelet activation and aggregation .the fast dissolving tablets of clopidogrel were prepared employing different concentrations of crospovidone and croscarmellose sodium in di...

environmental pollution by 2,4-dicholorphenol (2,4-dcp), commonly found in industrial wastewater has been a concern for humans over the past 50 years. garden radish peroxidase (grp) can eliminate this poisonous pollutant. the aim of this study was to apply an experimental response surface methodology (rsm) and central composite design (ccd) to optimize grp-based treatment in order to maximize ...

We present an approach to uncertainty propagation in dynamic systems, exploiting information provided by related experimental results along with their models. The approach relies on a solution mapping technique to approximate mathematical models by polynomial surrogate models. We use these surrogate models to formulate prediction bounds in terms of polynomial optimizations. Recent results on po...

in this study, thermoplastic polyolefin elastomeric (tpo) nanocomposites were fabricated by friction stir processing. the effect of different pin geometries on clay dispersion and mechanical properties of the tpo nanocomposite reinforced with 3% wt nanoclay has been first investigated. the optimum pin geometry namely threaded cylindrical pin was then used to fabricate the nanocomposites contain...

Local polynomial estimators are popular techniques for nonparametric regression estimation and have received great attention in the literature. Their simplest version, the local constant estimator, can be easily extended to the errors-in-variables context by exploiting its similarity with the deconvolution kernel density estimator. The generalization of the higher order versions of the estimato...

We consider goodness-of-fit tests with i.i.d. samples generated from a categorical distribution (p1, ..., pk). We test the null hypothesis whether pj = qπ(j) for some label permutation π. The uncertainty of label permutation implies that the null hypothesis is composite instead of being singular. In this paper, we construct a testing procedure using statistics that are defined as indefinite int...

The He I multiplet at 10830Å is formed in the incomplete Paschen-Back regime for typical conditions found in solar and stellar atmospheres. The positions and strengths of the various components that form the Zeeman structure of this multiplet in the Paschen-Back regime are approximated here by polynomials. The fitting errors are smaller than ∼10 −2 m ˚ A in the component positions and ∼10 −3 in...

The purpose of this study is to build up mathematical models to age specific marital fertility rates (ASM FRs) and forward cumulative ASM FRs of Bangladesh. For this, the secondary data of ASMFRs have been taken from Bangladesh Demographic and Health Survey (BDHS). It is observed that ASMFRs follows quadratic polynomial model in 1996 and one degree polynomial model i. e. simple linear regressio...

The asymptotic covariance matrices of the corrected score, the quasi score, and the simple score estimators of a polynomial measurement error model have been derived in the literature. Here some alternative formulas are presented, which might lead to an easier computation of these matrices. In particular, new properties of the variables tr and μr that constitute the estimators are derived. In a...

Most existing models of Stackelberg security games ignore the underlying topology of the space in which targets and defence resources are located. As a result, allocation of resources is restricted to a discrete collection of exogenously defined targets. However, in many practical security settings, defense resources can be located on a continuous plane. Better defense solutions could therefore...