The health benefits of purple sweetpotato, which is used as an edible food in its natural 13 state and in processed foods and as a natural color pigment, have been recognized. In Japan, 14 sweetpotato has been economically produced in regions below 36°4′N latitude, however, cultivation 15 areas are beginning to expand further north. The anthocyanin and polyphenolics in purple 16 sweetpotatoes c...

Type 2 diabetes (T2D) is characterised by hyperglycaemia resulting from defective insulin secretion, insulin resistance, or both. The impact of over-nutrition and reduced physical activity, evidenced by the exponential rise in obesity and the prevalence of T2D, strongly supports the implementation of lifestyle modification programs. Accordingly, an increased consumption of fruits and plant-deri...

The concept of prevention of cancer using naturally occurring substances that could be included in the diet consumed by the human population is gaining increasing attention. Tea, next to water, is the most popularly consumed beverage in the world and it is grown in about 30 countries. Abundant data, amassed from several laboratories around the world in the last ten years, provided convincing ev...

Introduction Phenolic compounds are important phytonutrients that are ubiquitously distributed throughout the plant kingdom. These compounds are associated with the sensory and nutritional quality of fresh and processed plant foods. Several varieties of dry beans {Phaseolus vulgaris L.) varying in seed shape, size, and color are consumed throughout the world primarily as an important source of ...

Opportunistic mycoses increase the morbidity and mortality of immuno-compromised patients. Five Candida species have been shown to be responsible for 97% of worldwide cases of invasive candidiasis. Resistance of C. glabrata and C. krusei to azoles has been reported, and new, improved antifungal agents are needed. The current study was designed to evaluatethe activity of various polyphenolic com...

Natural polyphenols have been reported to exert beneficial effects in preventing cardiovascular diseases but their neuroprotective mechanisms were studied much less. The review is focused on biochemical pathways and molecular neuroprotective mechanisms of natural polyphenols in the brain particularly; of course in close relation to neurophysiological and pathophysiological consequences. This re...

A modular strategy for the synthesis of hexacyclic dimeric resveratrol polyphenolic benzofurans is reported. The developed synthetic technology was applied to the total synthesis of malibatol A, shoreaphenol, and other biologically relevant poly-phenols.

many studies indicate that oxidative stress is involved in the pathophysiology of neurodegenerative diseases. oxidative stress can induce neuronal damages, modulate intracellular signaling and ultimately leads to neuronal death by apoptosis or necrosis. to review antioxidants preventive effects on oxidative stress and neurodegenerative diseases we accumulated data from international medical jou...

BACKGROUND Alzheimer's disease (AD) is a progressive neurodegenerative disorder clinically characterized by loss of memory and cognition. The effective therapeutic options for AD are limited and thus there is a demand for new drugs. Aegle marmelos (Linn.) (A. marmelos) leaves have been used in traditional medicine to promote intellect and enhance memory. In this study, we evaluated A. marmelos ...