Oligo(epsilon-caprolactone) and oligolactide were synthesized via ring-opening polymerization of cyclic esters in the presence of creatinine as initiators. Thus obtained oligomers were successfully used in the synthesis of novel polyurethane conjugates of norfloxacin. The structures of the polymers and conjugates were elucidated by means of MALDI-TOF MS, NMR and IR studies.

in order to prepare polyurethane elastomers with acceptable physical properties and good biocompatibility, novel polyurethane networks were synthesized via curing reaction of epoxy-terminated polyurethane prepolymers (eups) with hexamethylene diamine. eups were prepared from reaction of glycidol with nco-terminated polyurethanes (itps). itps were also synthesized from reaction of one equivalent...

Calcium phosphate ceramics are widely used as bone substitutes since they are biocompatible and bioactive. Having a chemical composition close to natural bone, calcium phosphate ceramics are promising bone substitute materials in orthopaedics, maxillofacial surgery and dentistry. Hydroxyapatite (HA) and tricalcium phosphate (TCP) are the most commonly used calcium phosphates, because their calc...

CONTEXT Condoms made of latex are not comfortable or appropriate for all consumers. Polyurethane condoms may provide a needed alternative. METHODS In a double-masked study, 805 monogamous couples were randomized to use either the polyurethane condom or the latex condom for six months. Couples recorded the frequency of intercourse, of condom use and of breakage and slippage throughout the tria...

BACKGROUND Polyurethane coating of breast implants has been shown to reduce capsular contracture in short-term follow-up studies. This 30-year study is the longest examination of the use of polyurethane-coated implants and their correlation with capsular contracture. METHODS This study evaluates the senior surgeon's (F.D.P.) experience with the use of polyurethane-coated implants in aesthetic...

Sutureless skin closure employing a new product ‘Polyurethane membrane’ (opsite) was evaluated in North Surgical Unit, Mayo Hospital Lahore in comparison with the standard technique of skin closure using interrupted silk stitches. The trial was conducted on 1 20 patients undergoing elective and emergency surgery. The results were comparable in both cases. Polyurethane skin closure yielded equal...

New antimicrobial polymer composite based on commercial polyurethane (PU) Laripur®LPR9020 and polymeric biocide polyhexamethylene guanidine hydrochloride (PHMG-Cl) has been prepared by solvent casting method. Modified PU films containing from 1 to 4 wt% of PHMG-Cl were characterized in terms mechanical, thermal surface properties, release behavior, as well antibacterial activity against Gram-ne...