نتایج جستجو برای: porphyria cutanea tarda

تعداد نتایج: 4335  

2014
Anne Taegtmeyer Alexandra Raetz Bravo Barbara Zimmermanns Evangelia Liakoni Stephan Kraehenbuehl Manuel Haschke

Methods We examined cases of DRESS syndrome which were reported to our pharmacovigilance centre 2008-2013 and cases reported in the literature during the same period for which CRP and/or PCT were available. Peak values were recorded whenever possible. The extent of CRP and PCT elevation in cases where DRESS syndrome was not due to antibiotics was also studied as these cases were less likely to ...

Journal: :The Journal of biological chemistry 1959
T C CHU E J CHU

Hepta-, hexa-, and pentacarboxylic porphyrins have been detected in porphyric as well as normal urine samples. From the former they have been isolated and converted into pure methyl esters (1). For a better understanding of the chemistry of these porphyrins, pure uroporphyrin I and uroporphyrin III were separately subjected to decarboxylation under controlled conditions. The decarboxylation pro...

2011
Marie Birk Jørgensen John Ektor-Andersen Gisela Sjøgaard Andreas Holtermann Karen Søgaard

BACKGROUND Cleaners constitute a job group with poor health and low socioeconomic resources. Therefore, there is a great need for scientifically documented health promoting initiatives for cleaners. However, both workplace initiatives and high quality intervention studies are lacking. The aim of this study was to evaluate the effects of a 3-month workplace trial with interventions to improve ph...

Journal: :BMC Public Health 2008
Fiona Reynolds Debbi L Stanistreet

BACKGROUND The aim was to examine any differences in the way that Read codes are applied to the records for female patients with learning disabilities across three PCT areas. To ascertain the most commonly used read codes for learning disability. METHODS This was a retrospective cohort study carried out in Bury, Heywood-and-Middleton and Rochdale PCTs. All women in the eligible age-group (25-...

2012
Dominik Zenner Darko Molinar Tom Nichols Johanna Riha Mary Macintosh Anthony Nardone

BACKGROUND Patient financial incentives ("incentives") have been widely used to promote chlamydia screening uptake amongst 15-24 year olds in England, but there is scarce evidence of their effectiveness. The objectives of the study were to describe incentives used to promote chlamydia screening in Primary Care Trusts (PCTs) in England and to evaluate their impact on coverage and positivity rate...

2017
Luís Coelho

With these limitations, researchers and clinicians look at the inflammatory cascade for a potential objective serum marker of infection. By definition a serum marker should be absent if the patient is not infected, appear concomitantly and ideally precede the clinical manifestations of infection, disappear with successful therapy or remain elevated if infection is refractory to treatment. Seria...

Journal: :Journal of structural biology 2014
Maxim Shatsky Pablo Arbelaez Bong-Gyoon Han Dieter Typke Steven E Brenner Jitendra Malik Robert M Glaeser

Tilted electron microscope images are routinely collected for an ab initio structure reconstruction as a part of the Random Conical Tilt (RCT) or Orthogonal Tilt Reconstruction (OTR) methods, as well as for various applications using the "free-hand" procedure. These procedures all require identification of particle pairs in two corresponding images as well as accurate estimation of the tilt-axi...

Journal: :Contemporary clinical trials 2012
Kenneth G Saag Penny E Mohr Laura Esmail Amy S Mudano Nicole Wright Timothy Beukelman Jeffrey R Curtis Gary Cutter Elizabeth Delzell Lisa C Gary T Michael Harrington Swapna Karkare Meredith L Kilgore Cora Elizabeth Lewis Rachael Moloney Ana Oliveira Jasvinder A Singh Amy Warriner Jie Zhang Marc Berger Steven R Cummings Wilson Pace Daniel H Solomon Robert Wallace Sean R Tunis

Pragmatic clinical trials (PCTs) seek to improve the generalizability and increase the statistical power of traditional explanatory trials. They are a major tenet of comparative effectiveness research. While a powerful study design, PCTs have been limited by high cost, modest efficiency, and limited ability to fill relevant evidence gaps. Based on an American Reinvestment and Recovery Act (ARRA...

2010
N Blundell A Clarke N Mays

AIM To explore interpretations of "appropriate" and "inappropriate" elective referral from primary to secondary surgical care among senior clinical and non-clinical managers in five purposively sampled primary care trusts (PCTs) and their main associated acute hospitals in the English National Health Service (NHS). METHODS Semi-structured face-to-face interviews were undertaken with senior ma...

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