Human corneal endothelial cells (HCECs) do not replicate after wounding. Therefore, corneal endothelial deficiency can result in irreversible corneal edema. Descemet stripping automated endothelial keratoplasty (DSAEK) allows selective replacement of the diseased corneal endothelium. However, DSAEK requires a donor cornea and the worldwide shortage of corneas limits its application. This review...

Custom high-resolution high-speed anterior segment spectral domain Optical Coherence Tomography (OCT) was used to characterize three-dimensionally (3-D) corneal topography in keratoconus before and after implantation of intracorneal ring segments (ICRS). Previously described acquisition protocols were followed to minimize the impact of the motions of the eye. The collected set of images was cor...

BACKGROUND The aim of the present study was assessing the possibility of experimental allogenic transplantation of cat cornea endothelial cells, multiplied in vitro, into the anterior chamber of the eyeball in recipient cats. The reason for undertaking the research is the need to develop a method that would help in the cornea treatment in animals with corneal opacification following cataract su...

BACKGROUND The cornea is responsible for two-thirds of the eye's refractive power which is a function of the shape and refractive index. The aim of this present study is to examine human eyes in vivo for corneal shape changes in response to short-term elevation in intraocular pressure. METHODS Videokeratographic and tonometric assessments at baseline were compared with the same assessments wh...

Corneal transplantation, as full-thickness transplantation, is an old surgical procedure which has been successfully performed for more than 100 years. However, in a last decade significant changes in surgical technique(s) have been implemented. The reason for such changes is the current trend to replace only the diseased part of the recipient cornea, not the whole cornea. Therefore, if the ant...

BACKGROUND Keratoconus (KC) is usually a bilateral corneal ectatic disease. For significant asymmetric presentation (so called unilateral KC), the fellow eye has the mildest and earliest form of the disease, which is typically called forme fruste keratoconus. The aim of this study was to evaluate the sensitivity and specificity of parameters derived from a Scheimpflug imaging system (Pentacam) ...

Recently, two papers "Dorronsoro et al., Experiment on PMMA models to predict the impact of corneal refractive surgery on corneal shape, Opt. Express 14, 6142 (2006)" and "JR Jiménez et al., Deviations of Lambert-Beer's law affect corneal refractive parameters after refractive surgery, Opt. Express 14, 5411 (2006)" have been published on an important question in corneal refractive surgery: to e...

OBJECTIVE To assess the frequency of corneal dystrophies on the basis of histopathology in surgically-removed corneas. METHODS The descriptive study was conducted at Foundation University Medical College, Islamabad, and Al Shifa Eye Hospital, Rawalpindi, Pakistan, from May to October 2011, and comprised post-keratoplasty corneal specimen irrespective of age and gender. The surgically-removed ...