23 The analyses reported in Table 1 indicate that the fragment I used by us had 7 or 8, rather than 6 disulfide bonds, leading to an even lower probability for return to the native structure by random reoxidation. 24 Anfinsen, C. B., E. Haber, M. Sela, and F. H. White, Jr., these PROCEEDINGS, 47, 1309 (1961). 25 Chen-Lu, T., D. Yu-Cang, and X. Geng-Jun, Sci. Sinica (Peking), 10, 332 (1961); see...

'Darwin is the greatest of all scientists, greater even than Newton or Einstein, and I am quite certain that my own thinking has been more deeply influenced by the evolutionary concepts of Darwin than by anything else' (Burnet, 1966). 'Life must have begun as some particular configuration of atoms, an inconceivably tiny knot of molecular structure, which by some freak of circumstance was able t...

The Fourth International Symposium on Respiratory Viral Infections was convened by The Macrae Group (New York, NY) in Curaçao, Netherlands Antilles on 29 November–2 December, 2001. This symposium provides an annual forum for virologists, vaccinologists, clinicians, pharmacologists, and public health specialists to discuss recent advances in respiratory virus research in an interdisciplinary fas...

Burnet (1938) and Cox and Bell (1939) cultivated Coxiella burnetii in tissue cultures of the Maitland type. Burnet reported satisfactory results with cultures of pooled chick embryo viscera, but not with skeletal or nervous tissues or single viscera. Cox and Bell noted that, of the chick embryo tissues, yolk sacs yielded best and most consistent growth. However, in both series of experiments, m...