The preface to the 6th edition of Human Nutrition and Dietetics (Davidson & Passmore, 1975) begins with the statement that ‘At the present time a knowledge of nutrition is of growing importance because of the increase in world population. In 1974 the World Food Conference in Rome (United Nations, 1975) and the World Population Conference in Bucharest (United Nations, 1974) reflected the concern...

Mackay and Burnet's Autoimmune diseases, published in 1962, marked the beginning of autoimmunity as a clinical science and led to the future acceptance of the existence of autoimmunity. While there is still controversy regarding the mechanisms of autoimmunity, the authors' insightful hypothesis based on clonal selection theory and the emergence of "forbidden clones", due to somatic mutations, i...

For more than 100 years, the germ theory of cancer, proposing that microorganisms were at the origin of the disease, dominated medicine. Several eminent scientists like Etienne Burnet, Mikhail Stepanovich Voronin, Charles-Louis Malassez, and Francis-Peyton Rous argued on the pathogenesis presenting their theories that implicated cocci, fungi and parasites. The impact of these theories was culmi...

The adaptive immune system has been the core of immunology for the past century, as immunologists have been primarily focused on understanding the basis for adaptive immunity for the better part of this time. Immunological thought has undergone an evolution with regard to our understanding as the complexity of the cells and the molecules of the system became elucidated. The original immunologis...

Sanguisorbae radix (SR), the root of Sanguisorba officinalis L. (Rosaceae), has been traditionally used for its anti-inflammatory, anti-infectious and analgesic activities in Korea. Previous work has shown that SR prevents neuronal cell damage induced by Abeta (25--35) in cultured rat cortical neurons. The present study was carried out to further investigate the neuroprotective effect of SR on ...

We prove that, given integers l, q ≥ 2 and n there exists an integer α such that, if M is a simple matroid with no l + 2point line minor and at least αq elements, then M contains a PG(n− 1, q′)-minor, for some prime-power q′ > q.

Helitropium europaeum L. population Garmsar was shown to contain three major alkaloids: heliotrine N-oxide (2), lasiocarpine (4) and lasiocarpine N-oxide (5); and four minor alkaloids: heliotrine (I), europine (3), acetyllasiocarpine (6) and a novel alkaloid acetyllasiocarpine N-oxide (7).