Timothy M. Crowder, PhD, is chief technology officer at Oriel Therapeutics, Inc., PO Box 14087, Research Triangle Park, NC 27709, tel. 919.313.1290 ext. 11, fax 919.313.1295, [email protected]. ctive dry-powder inhalers (DPIs) for pulmonary drug delivery have been under development for at least 10 years, but to date no such device has been approved by FDA. Like propellant-driven me...

The nasal absorption of macromolecules from powder formulations and the effect of sodium carboxymethyl cellulose (CMC-Na) as a pharmaceutical excipient on their absorption were studied. Model macromolecules were fluorescein isothiocyanate-labeled dextran (average molecular weight of 4.4kDa, FD4) and insulin. The plasma concentration of FD4 after application of the powder containing 50% starch (...

The purpose of the present study was to evaluate the effects of red pepper seeds powder on lipid metabolism in rats fed high fatᆞhigh cholesterol diet. Rats were divided into five experimental groups: normal diet group, high fatᆞhigh cholesterol diet group, high fatᆞhigh cholesterol diet with 5% red pepper seeds powder supplemented group (SA group), high fatᆞhigh cholesterol diet with 10% red p...

mold powders used in the continuous casting of steel contain the harmful caf2 as a main substance developing toxic gases such as sif4 and hf at elevated temperatures. in this study, three samples of i1, i2 and i3, which contained gypsum free portland cement clinker with different percentages of fe2o3 (5.68, 6.83, 8.02 ) and f- (2.09, 1.06, 0), were prepared and their main characteristics were c...

Within the framework of responsible mining, a SOLSA project (www.solsa-mining.eu) to develop an in-situ tool allowing a quick mineralogical identification of site drill cores has been recently launched. Its objective is to develop new or improved highly-efficient and cost-effective, sustainable exploration technologies. It combines and integrates nondestructive sensors: X-ray fluorescence, X-ra...

Thermochemcial characteristics of powder fabricated using oxidation treatment of spent PWR fuel and SIMFUEL were evaluated for recycling of spent fuel such as DUPIC process. Especially, the influence of spent fuel burn-ups on the powder fabrication characteristics was experimentally evaluated, ranging from 27,300 to 65,000 MWd/tU. Densities of powder manufactured from an oxidation, OREOX and th...

Table S1. Crystal data and structure refinement.......................................... ....................................S2 Figure S1. Powder EPR spectra of 1•2[Al(ORF)4] at various temperatures (120-170K)..............................S3 Figure S2. Powder EPR spectra of 1•2[Al(ORF)4] at various temperatures (190-290K)... ...........................S4 Figure S3. Powder EPR spectrum of 1•2[A...

Solid-state fermentation was carried out using jackfruit seed powder as substrate for the production of pigments using a fungal culture of Monascus purpureus. Due to the buffering nature of jackfruit seed powder, colour of pigments produced was stable over a wide range of initial pH of the substrate. Jackfruit seed powder with a particle size between 0.4 and 0.6 mm without any additional carbon...

Interface instability (or s̀ausaging’) has been a major problem in the oxide powder-in-tube tape-rolling process. The fast Fourier transform of core instabilities are ® rst performed to study the rolled tapes and to obtain quantitative information on the wavelengths and magnitudes of the nonuniform pro® les. The existing experimental observations are also re-examined and summarized. Treating thi...