Adrenocortical carcinoma (ACC) is a very aggressive tumor with a poor prognosis. Available treatments for this type of cancer are far from being satisfactory. The IGF signalling pathway represents an important mechanism for ACT growth and constitutes a relevant therapeutic target. We investigated the effect of picropodophyllin (PPP), a member of the cyclolignan family and a new inhibitor of IGF...

Most of the international asset pricing models are developed in the situation where purchasing power parity (PPP) is not respected.Investors of different countries do not agree on expected security returns. However, in this case, an equilibrium on the international assets market may exist but not on the international goods market. Our purpose in this paper is to give conditions under which we h...

As use of autologous platelet-rich plasma (PRP) and platelet-poor plasma (PPP) increases for intraoperative care of a variety of patients, it is important for perioperative nurses to recognize their benefits. Autologous PRP may decrease postoperative drainage, reduce narcotic requirements, and facilitate an early return to mobility. Postoperatively, patients should experience fewer complication...

it is found for the last two decades that there has been a rapid rise of ppps across the world. a government in developing countries like india is using ppp arrangements for improved delivery of infrastructure services and social services. public private partnerships which are an integral part of the new paradigm of good governance policy is the most recent addition in the world of society and ...

Research has demonstrated that receiver clock modeling can reduce the correlation coefficients among the parameters of receiver clock bias, station height and zenith tropospheric delay. This paper introduces the receiver clock modeling to GPS/GLONASS combined precise point positioning (PPP), aiming to better separate the receiver clock bias and station coordinates and therefore improve position...

(E)-3-Phenyl-1-(2-pyrrolyl)-2-propenone (PPP) is a pyrrole derivative of chalcone, in which the B-ring of chalcone linked to β-carbon is replaced by pyrrole group. While pyrrole has been studied for possible Src inhibition activity, chalcone, especially the substituents on the B-ring, has shown pharmaceutical, anti-inflammatory, and anti-oxidant properties via inhibition of NF-κB activity. Our ...

Abstract The presentation-practice-production (PPP) approach is used in primary schools Vietnam to teach speaking skills. However, there disagreement about the theoretical validity and practical efficacy of PPP ( Ellis, 2018 ; Willis & Willis, 2007 ) little research evidence for how teachers actually implement their views this approach. current study addresses gap. Seven from six were obser...

background:the utility and efficacy of novel materials in tissue regeneration and antimicrobial therapy are contingent upon the employment of either blood derivatives rich in platelets or platelet-poor-plasma (ppp). this effect is largely mediated by the increased or decreased concentration of platelets in the plasma. the current study aimed to analyze and evaluate the impact of platelet-rich (...

OBJECTIVE Recent publications demonstrated improved outcomes during cardiac surgery when platelet rich plasma (PRP and platelet poor plasma (PPP) were applied during closure of the sternal and leg wounds [1,2]. These studies indicate a potential utility for PRP and PPP application in cardiothoracic surgery; however, further studies are necessary to truly measure the clinical efficacy of this in...

We present a case of palmoplantar pustulosis (PPP) secondary to olfactory cleft inflammation in a 65-year-old man. He had a 10-year history of PPP. Computed tomography showed an abnormal intensity that corresponded to chronic inflammatory sinusitis in the right maxillary and ethomoidal sinuses, and obstruction of the olfactory cleft. After administration of intranasal steroid drops, the olfacto...