Polymorphisms within interleukin-1 (IL1) and tumor necrosis factor alpha (TNFA) gene clusters are associated with an increased risk of gastric cancer. However, their role in gastric precancerous lesions remains poorly understood. Our objective was to perform a meta-analysis of studies addressing the association between IL1B-511, IL1RN variable number of tandem repeat, and TNFA-308 gene polymorp...

aim : the aim of this study was to report the anatomical location and histologic type of colorectal polyps in a large series of iranian patients that attended for colonoscopy. background : polyps that develop through the adenoma-carcinoma pathway are considered neoplastic and may eventually progress to invasive carcinomas. in addition polyps can develop with no neoplastic potential. these neopl...

The aim of the study: present study is to evaluate accuracy fine needle aspiration cytology (FNAC) thyroid swellings and correlate with histopathological findings avoid unnecessary surgeries for benign lesions.
 Methods: this a prospective study. A total 55 cases were studied in Department Pathology at A.C.S Medical College Hospital. Fine was done correlated examination. Sensitivity, speci...

Introduction: Cervical cancer is a huge emotional and financial burden on society. To curb the disease, there is a need to develop a screening test that has good sensitivity and specificity. The present study is aimed to compare the effectiveness of the Pap smear, Visual Inspection with Acetic Acid (VIA) for mass screening of premalignant and malignant lesions of the cervix. Aims and objectives...

Background: Phosphoactivation of a DNA damage response molecule checkpoint kinase 2 (pChk2) may be a marker of oral epithelial cells that have entered the precancerous and squamous cell carcinoma (SCC) stages. We explored whether there was selective expression of pChk2 in precancerous lesions but not in nonneoplastic tissue of the oral mucosa. Experimental Design: In a retrospective cohort desi...

Background: Ovary is the commonest site of neoplastic and non-neoplastic lesion, can present in childhood to postmenopausal age group accounts for most prevalent cause hospital admissions. Aims & Objectives: (1) To know about various histopathological types ovarian lesions presented diagnosed. (2) study incidence with respect patient’s age. (3) frequency terms or neoplastic, benign malignant, u...

With improved overall survival of cervical cancer patients, the importance of the quality of life (QOL) is increasingly recognized. This study was conducted to compare the QOL of women with different stage cervical cancer before and after treatment to facilitate improved cervical cancer prevention and treatment. We used the generic Medical Outcomes Study Short Form-36 (MOS SF-36) to collect QOL...

Oral squamous cell carcinomas develop in precancerous fields consisting of genetically altered mucosal epithelial cells. These precancerous fields may appear as clinically visible lesions, in particular, oral leukoplakia, but the large majority remains clinically undetectable. The aim of this study was to assess the potential value of a noninvasive screening approach to detect precancerous fiel...