نتایج جستجو برای: predictionnearest shrunken centroid
تعداد نتایج: 9551 فیلتر نتایج به سال:
OBJECTIVES Understanding value provides an important context for improvement. However, most health care models fail to measure value. Our objective was to categorize inpatient encounters within an academic congenital heart program based on clinical outcome and the cost to achieve the outcome (value). We aimed to describe clinical and nonclinical features associated with value. DESIGN We defin...
In recent years we have seen a tremendous growth in the volume of text documents available on the Internet, digital libraries, news sources, and company-wide intranets. Automatic text categorization, which is the task of assigning text documents to pre-specified classes (topics or themes) of documents, is an important task that can help both in organizing as well as in finding information on th...
Lysophosphatidyl acyltransferase (LPAAT) is a pivotal enzyme controlling the metabolic flow of lysophosphatidic acid into different phosphatidic acids in diverse tissues. A search of the Arabidopsis genome database revealed five genes that could encode LPAAT-like proteins. We identified one of them, LPAAT1, to be the lone gene that encodes the plastid LPAAT. LPAAT1 could functionally complement...
In the present study, we systematically investigated population differentiation of drug-related (DR) genes in order to identify common genetic features underlying population-specific responses to drugs. To do so, we used the International HapMap project release 27 Data and Pharmacogenomics Knowledge Base (PharmGKB) database. First, we compared four measures for assessing population differentiat...
New statistical procedures are introduced to investigate gene activity in support of the hypothalamus–pituitary– gonad–liver signaling network that provides the neuroendocrine regulation for reproduction in female, oviparous fishes. The methods include Shrunken Centroid Ordering by Orthogonal Projections (SCOOP) and a robust encoding of B-splines via Friedman’s Generalized Elastic Net (GEN). SC...
BACKGROUND Oesophageal cancer is one of the most deadly forms of cancer worldwide. Long non-coding RNAs (lncRNAs) are often found to have important regulatory roles. OBJECTIVE To assess the lncRNA expression profile of oesophageal squamous cell carcinoma (OSCC) and identify prognosis-related lncRNAs. METHOD LncRNA expression profiles were studied by microarray in paired tumour and normal ti...
In the title compound, C(29)H(22)O(4), the chromene ring is almost planar with a small puckering [0.143 (2) Å]. The crystal structure is stabilized by C-H⋯O and C-H⋯π inter-actions. Edge-to-face (centroid-centroid distances of 3.894 and 3.673 Å) and face-to-face (centroid-centroid distance of 3.460 Å) π-π-ring electron inter-actions are also observed.
In either of the two independent mol-ecules within the asymmetric unit of the title compound, [Ni(C(16)H(15)NO(3))(C(3)H(4)N(2))], the Ni(II) atom is coordinated by the two N atoms and two O atoms in a distorted square-planar geometry. The crystal packing is stabilized by strong and weak inter-molecular C-H⋯O hydrogen bonds, as well as weak centroid-centroid π-stacking inter-actions [centroid-c...
Using the spatial cueing technique, this study demonstrates that the center of mass (centroid) of a visual scene has a special ability to attract attention even when there is no object presented at this location. Four boxes formed an imaginary square and were presented to the left or right hemifield. After the cueing in one box, a target appeared in one of the four boxes and, in addition, at ce...
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