The application of inhibitors of the Rho kinase pathway (ROCK inhibitors) to the surface of the eye in the form of eyedrops has beneficial effects which aid the recovery of diseased or injured endothelial cells that line the inner surface of the cornea. The aim of this study was to test the plausibility of delivering a selective ROCK inhibitor, Y-27632, to the cornea using a thin polymeric film...

In this paper the effect of various chemical treatments on the damping property of jute fiber reinforced green composite is discussed. The surface of the jute fiber was modified by alkali, permanganate, benzoyl chloride, malic anhydride and silane treatments. Several samples of unidirectional composites were prepared with treated jute fibers as well as untreated jute fibers. Matrix used is epox...

The vermiculite mine in Libby, Montana, was in operation for over 70 yr and was contaminated with asbestos-like amphibole fibers. The mining, processing, and shipping of this vermiculite led to significant fiber inhalation exposure throughout the community, and residents of Libby have developed numerous pulmonary diseases such as lung cancer and mesothelioma. The present study describes the sep...

The release of arsenic from wood pressure-treated with chromated copper arsenate (CCA) can be decreased by application of wood finishes, but little is known about the types of finishes that are best suited for this purpose. This study evaluated the effects of finish water repellent content and ultraviolet (UV) radiation on the release of arsenic, copper, and chromium from CCA-treated wood expos...

OBJECTIVE To analyze morphological characteristics and organization of the collagen fibers of third degree burns from scalding compared to laser therapy and silver sulfadiazine, the latter considered as the gold standard. METHOD Were selected 12 animals (Rattus norvegicus) also divided into three groups (control group [CG] - untreated burns; sulfadiazine group [SG] - burns were treated with s...

The shift of paradigm in combinatorial chemistry, from large compound libraries (of mixtures) on a small scale towards defined compound libraries where each compound is prepared in an individual well, has stimulated the search for alternative separation approaches. The key to a rapid and efficient synthesis is not only the parallel arrangement of reactions, but simple work-up procedures so as t...

extended-release matrix tablets of diltiazem hydrochloride (dtz) were prepared using waxy materials alone or in combination with kollidon sr. matrix waxy materials were carnauba wax (cw), bees wax (bw), cetyl alcohol (ca) and glyceryl monostearate (gms). dissolution studies were carried out by using a six stations usp xxii type 1 apparatus. the in vitro drug release study was done in 1000 ml ph...

The polysaccharides and proteins of various seeds have bioflocculant properties. The performance of naturally occurring Strychnos potatorum was evaluated against the chemical coagulant alum. The study involved extensive jar test experiments using Strychnos potatorum suspension and alum solution either independently or in combination with spiked turbid water prepared in the laboratory. It was ob...

determination of 1, 1-dimethylhydrazine (dmh) in air is carried out by spectrophotometry, gc or hplc analysis, but in this study dmh was analyzed by a gas sensor based on nanostructure conducting polyaniline. determination of dmh has been done very simplely and quickly in recent work. electrically conductive fibers have been prepared by polymerization of aniline on surfaces of commercial polyme...

BACKGROUND Development of a nanosized polymeric delivery system for erlotinib was the main objective of this research. MATERIALS AND METHODS Poly caprolactone-polyethylene glycol-polycaprolactone (PCEC) copolymers with different compositions were synthesized via ring opening polymerization. Formation of triblock copolymers was confirmed by HNMR as well as FT-IR. Erlotinib loaded nanoparticles...