OBJECTIVE To review the use of airway pressure release ventilation (APRV) in the treatment of acute lung injury/acute respiratory distress syndrome. DATA SOURCE Published animal studies, human studies, and review articles of APRV. DATA SUMMARY APRV has been successfully used in neonatal, pediatric, and adult forms of respiratory failure. Experimental and clinical use of APRV has been shown ...

Hypertension is associated with increased risk of thrombotic events including myocardial infarction and stroke. The endothelium plays an important role in limiting intravascular thrombosis, inhibiting coagulation and platelet aggregation, and promoting fibrinolysis. Hrafnkelsdottir et al1 have previously described impaired vascular tissue-type plasminogen activator (t-PA) release in individuals...

The nite-di erence time domain (FDTD) method provides a simple and accurate means of simulating a wide range of acoustic wave propagation problems. Unfortunately, the method has a voracious appetite for computational resources. For example, to accurately model scattering from a continuously varying pressure-release boundary, an FDTD grid is typically required that has a much ner discretization ...

In an isolated dog heart, perfused with blood from an anesthetized donor, left ventricular performance was observed during periods in which the left ventricle either contracted isovolumically or was allowed to eject saline. Heart rate and left ventricular end-diastolic pressure were comparable in both. Ventricular performance, as judged by peak systolic ventricular pressure, declined relatively...

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This paper considers the statistical properties of the waves generated by a point source in the subsurface and transmitted towards the surface through a randomly layered medium. The problem is analyzed in a regime of separation of scales and with pressure release boundary conditions at the surface. Using a probabilistic representation of the spectral density of the waves received at the surface...

in the present study, floating drug delivery beads (fdds) were prepared with sodium alginate/ starch blend as a matrix, sodium hydrogen carbonate as a pore forming agent, methyl cellulose as a binder and barium chloride solution as a hardening agent. in order to prepare the beads with different porosity and morphology the ratio between pore forming agent to polymer blend and ratio of the consti...

STUDY OBJECTIVE We hypothesized that the continuous gas flow administration delivered through an insufflation catheter positioned above the carina during airway pressure release ventilation (APRV) would facilitate carbon dioxide (CO2) elimination, resulting in normocarbia with a substantially reduced peak airway pressure (Paw). To test this hypothesis, we compared intermittent positive pressure...

Release liners are part of a composite made of a label with its own adhesive on a release liner or carrier with its own release coating. The label comprises either a synthetic face stock such as polypropylene or paper. The adhesive is usually an organic material such as a polyacrylate or polyisoprene based rubber. The release liner can be made from various substrates treated with a suitable pro...

HYPOTHESIS Donor management with airway pressure release ventilation (APRV) improves oxygenation and increases lung donation while maintaining equivalent graft survival. DESIGN Retrospective case series. SETTING Private, tertiary care, level I trauma center. PATIENTS Forty-five consecutive organ donors. INTERVENTIONS Management with assist/control ventilation (ACV) or APRV. MAIN OUTCO...