In patients with diabetes mellitus (DM), chronic infections are frequent and severe due to the impairment of their immune status. However, data on the prevalence of Helicobacter pylori (H. pylori) infection in DM type II (DMT2) are scanty and contradictory. Aim of this study was to evaluate the prevalence of H. pylori infection in DMT2 patients in Northern region of India (Rajasthan state, more...

AIM To explore the association between Helicobacter pylori (H. pylori) infection and obesity/weight gain in a Chinese population. METHODS Our primary outcome was the change in body mass index (BMI). The generalized linear models were used to explore the association between H. pylori infection and the change of BMI, and the logistic regression models were used to explore the association betwee...

Background: The aim of the present study was to investigate the prevalence of resistance rate in Helicobacter pylori against commonly used antibiotics including tetracycline, metronidazole, clarithromycin, amoxicillin, ciprofloxacin, nitrofurantoin, erythromycin and rifampin in Iranian patients. Methods: H. pylori isolates were obtained from gastric biopsies from patients referred for upper gas...

CagA seropositivity is an important risk factor for gastric adenocarcinoma and duodenal ulcer. However, CagA seropositivity is also found in Helicobacter pylori-seronegative subjects. Is CagA seropositivity in these subjects a sign of a past H. pylori infection, or does it represent a false-positive reaction? This study investigates the intensity of the CagA immune reaction and the variation in...

Background and Aim: Helicobacter pylori (H. pylori) is a major human pathogen. Its role in the pathogenesis of portal hypertensive gastropathy is debated. The aim of this study was to evaluate the prevalence of this infection in patients with portal hypertension due to HCV-related liver cirrhosis, and its relation with the disease severity. Patients and Methods: 80 consecutive patients with HCV...

BACKGROUND Helicobacter pylori infection treatment was found not to reduce the prevalence of iron deficiency or anemia among Alaska Native children at 14 months after treatment initiation. We hypothesized that 14 months was to early to resolve H. pylori-induced gastric damage. Consequently, we conducted a 40-month follow-up. METHODS We enrolled 219 children 7-11 years old who had H. pylori in...

BACKGROUND The importance of sialic acid binding adhesin (sabA) as a new outer membrane protein in gastroduodenal diseases has been recognized. The prevalence rate of sabA gene varies in different geographic areas. OBJECTIVES The aim of this study was to determine the frequency of sabA gene in Helicobacter pylori (H. pylori) strains isolated from different clinical outcomes in Tehran, Iran. ...

Aims: The objective of this retrospective study was to evaluate the prevalence Helicobacter pylori (H. pylori) positivity, gastric atrophy, and intestinal metaplasia in patients with dyspeptic complaints who had undergone total hip knee replacement surgeries, compared a control group without prosthesis.
 Methods: consisted 51 prosthesis, while comprised 75 similar but prosthesis. Endoscopi...

Introduction: In addition to Helicobacter pylori, non-Helicobacter pylori helicobacters (NHPHs) have been diagnosed in the humans stomach that caused gastrointestinal diseases. This study aimed to evaluate the coinfection of H. pylori with NHPHs species in patients with gastric disorders in Iran.   Materials & Methods: This cross-sectional study was performed on 421 gastric biopsies form dysp...

Helicobacter pylori (H. pylori) has a role in the multifactorial etiology of peptic ulcer disease. A link between H. pylori infection and duodenal ulcer disease is now established. Other contributing factors and their interaction with the organism may initiate the ulcerative process. The fact that eradication of H. pylori infection leads to a long-term cure in the majority of duodenal ulcer pat...