The temporal and spatial distributions of primary and secondary organic carbon aerosols (OC) over the continental US from 15 June–31 August 1999, were estimated by using observational OC and elemental carbon (EC) data from Interagency Monitoring of Protected Visual Environments (IMPROVE) and Southeastern Aerosol Research and Characterization project (SEARCH) networks, coupled with the primary O...

This in dex cov ers all tech ni cal items pa pers, cor re spon dence, re views, etc. that ap peared in this pe ri od i cal dur ing 1999, and items from pre vi ous years that were com mented upon or cor rected in 1999. In the case of mag a zines, de part ments and other items may be also cov ered if they have been judged to have ar chi val value. The Au thor In dex con tains the pri mary en try ...

Research on applying RNA interference (RNAi) to counter HBV replication has led to identification of potential therapeutic sequences. However, before clinical application liver-specific expression and efficient delivery of these sequences remain an important objective. We recently reported short-term inhibition of HBV replication in vivo by using helper dependent adenoviral vectors (HD Ads) exp...

Since the virulence of a virus is usually multifactorial in both natural and experimental infections, it is of considerable interest to identify a situation in which a single genetic character controls virulence. Susceptibility or resistance to mouse hepatitis virus (MHV) 1 may be controlled by a single genetic character. In turn the genetic resistance of the Call mice to MHV Princeton strain (...

We call a right continuous increasing process Kx a partial right inverse (PRI) of a given Lévy process X if XKx = x at least for all x in some random interval [0; ) of of positive length. In this paper we give a necessary and su¢ cient condition for the existence of a PRI in terms of the Lévy triplet. AMS subject classi…cation. 60G51 Key words and phrases. Lévy process; ladder height subordinat...

MiR-124 functions as a tumor suppressor and plays an important role in tumorigenesis. A common polymorphism (rs531564, C>G) in the pri-miR-124 has been recently studied in connection with cancer risk. The aim of the present study was to investigate the association between pri-miR-124 rs531564 polymorphism and the risk and clinicopathological characteristics of colorectal cancer (CRC). Two case-...

Successful fertilization and subsequent embryo development rely on complex molecular processes starting with the development of oocyte competence through maturation. MicroRNAs (miRNAs) are small non-coding RNA molecules that function as gene regulators in many biological systems, including the oocyte and embryo. In order to further explore the roles of miRNAs in oocyte maturation, we employed s...

RESUME This paper describes the work currently being undertaken by researchers within the NERC Centre for Terrestrial Carbon Dynamics (CTCD) with CHRISProba data. The paper focuses on information extraction on crop and forest cover types over our two test sites (Barton Bendish and Harwood Forest). 1. A SPARSE INTERPOLATED LUT INVERSION The aim of the work over crop canopies has been to develop ...

The RNA-binding protein DiGeorge Critical Region 8 (DGCR8) and its partner nuclease Drosha are essential for processing of microRNA (miRNA) primary transcripts (pri-miRNAs) in animals. Previous work showed that DGCR8 forms a highly stable and active complex with ferric [Fe(III)] heme using two endogenous cysteines as axial ligands. Here we report that reduction of the heme iron to the ferrous [...

The Polycomb-group protein, Ezh2, is required for epigenetic gene silencing in the adult heart by unknown mechanism. We investigated the role of Ezh2 and non-coding RNAs in a mouse model of pressure overload using transverse aortic constriction (TAC) attenuated by the prototypical histone deacetylase inhibitor, trichostatin A (TSA). Chromatin immunoprecipitation of TAC and TAC+TSA hearts sugges...