The epidemiology of eye Disease, 3rd edition, edited by Johnson GJ et al. The third edition of this authoritative text is 240 pages longer than the previous version and has 15 additional expert contributors. There is an extra chapter on research synthesis and an expanded section on visual impairment and blindness in children. Dry eye and uveitis now feature as separate entities, and the final t...

PURPOSE To assess the level of plasma glutathione in patients with untreated primary open-angle glaucoma. METHODS Twenty-one patients with newly diagnosed primary open-angle glaucoma and 34 age- and gender-matched control subjects were subjected to a blood analysis to detect the level of circulating glutathione in its reduced and oxidized forms. The effect of age, gender, and systemic blood p...

AIMS To assess the Tuck-Crick and the Quigley-Vitale predictive regression equations against fresh independent real world data for estimating the prevalence of primary open angle glaucoma (POAG) in the UK. To apply the equations to the elderly population of England and Wales, for which there is sample survey data on glaucoma, and demographic data. METHODS Directly measured actual prevalence o...

[This corrects the article DOI: 10.1371/journal.pone.0191185.].

Secondary angle closure glaucomas are a distinct entity from primary angle closure glaucoma (PACG). Unlike PACG, secon­ dary angle closure glaucoma’s have an identifiable contributory factor/s for angle closure and obstruction of aqueous flow which is usually unrelieved by iridotomy. The treatment of each type of secondary angle closure glaucoma is varied, so identification of the primary cause...

The effective use of aqueous and oily pilocarpine was studied in 19 glaucomatous eyes. The aqueous drops were used 4 times a day while the oily drops were used only twice. It was found that the oily drops were better than the aqueous drops in lowering the mean intraocular pressure and the maximum pressure reached during the day. no statistically significant difference was found between the 2 pi...

AIMS To study the effect of axial length on the hypotensive effect of latanoprost in primary open angle glaucoma (POAG) in a prospective, observational study. METHODS The authors measured axial length and baseline intraocular pressure (IOP) of 109 eyes with POAG, and then repeated the IOP measurements at 1, 3, and 6 months after starting treatment with latanoprost. RESULTS The mean IOP leve...

A prospective trial was conducted of laser trabeculoplasty randomly assigned to one eye of a group of elderly patients with bilateral primary phakic open angle glaucoma who were already taking the maximum medical treatment that they could tolerate. With a minimum follow-up of 2 1/2 years (mean 35 months) a significant fall in mean intraocular pressure of over 7 mmHg (30%) at the time of the pat...

PURPOSE Considering that noncompliance to glaucoma treatment is one of the risk factors associated with disease s progression, the purpose of the present study was to evaluate: 1) knowledge and feelings about the disease; 2) self-reported noncompliance to treatment and related factors; and 3) influence of disease in lifestyle. METHODS Interviews, with application of a semi-structured question...