INTRODUCTION Globally, dementia is the most frequent form of degenerative condition in the older adult population and poses a major health burden with high socioeconomic costs. So far, attempts to find pharmacologic interventions that can change the onset or progression of dementia have been largely unsuccessful, prompting a shift to focus on interventions aimed at modifying risk factors that o...

BACKGROUND The feasibility of conducting a large-scale Polypill clinical trial in developing countries remains unclear. More information is needed regarding the efficacy in reducing the risk factors of cardiovascular disease (CVD), side effects, improvement in adherence and physician/patient "acceptability" of the Polypill. METHODS We conducted an open-label, parallel-group, randomized clinic...

The aim of cancer prevention is to develop methods, plans or policy for interventions that will benefit the population, as well as develop systems for monitoring and evaluating these interventions in the future. The purpose of interventions is to reduce the incidence, morbidity, mortality rates of cancer and cost of cancer management. Because the modes of interventions that will be employed inv...

PURPOSE The objective of this study was to elucidate the long-term prognosis of patients with implantable cardioverter-defibrillators (ICDs) in Korea. MATERIALS AND METHODS We enrolled 405 patients (age, 57.7±16.7 years; 311 men) who had undergone ICD implantation. The patients were divided into three groups: heart failure (HF) and ICD for primary (group 1, n=118) and secondary prevention (gr...