Background: The NASA Metrics Data Program data sets have been heavily used in software defect prediction experiments. Aim: To demonstrate and explain why these data sets require significant pre-processing in order to be suitable for defect prediction. Method: A meticulously documented data cleansing process involving all 13 of the original NASA data sets. Results: Post our novel data cleansing ...

AIMS Hazardous alcohol use is a leading cause of death among adolescents and young adults world-wide, yet few effective prevention interventions exist. This study was the first to examine a computerized harm minimization intervention to reduce alcohol misuse and related harms in adolescents. DESIGN Cluster randomized controlled trial of a six-session curriculum-integrated harm minimization pr...

abstract background: acute opium intoxication is one of the most common causes of poisoning in children in iran. although most cases are accidental, traditional misuse of opium for symptomatic therapy of various childhood diseases also contributes to high rate of opium intoxication in iran. cases: here, we report two cases of opium intoxication in infants resulted from transdermal application o...

Evidence of the misuse of dihydrocodeine preparations remains largely anecdotal,' 2consisting of case reports of dependence mainly among users of the proprietary form of dihydrocodeine tartrate DF 118. Recent estimates of the extent of dihydrocodeine misuse in the general population and among drug users are lacking. This paper reports the results of an investigation into the level of DF 118 mis...

In recent years, concentration on software design phase for evaluating security into the developing software increased where the cost of fixing errors in design level is several times less than the cost of fixing errors in the coding or implementation levels. One of the main challenges in facing current models that evaluate security into the software design phase refers to the need for existenc...

In biometrics, a human being needs to be identified based on some characteristic physiological parameters. Often this recognition is part of some security system. Secure storage of reference data (i.e., user templates) of individuals is a key concern. It is undesirable that a dishonest verifier can misuse parameters that he obtains before or during a recognition process. We propose a method tha...

BACKGROUND Overdose deaths have increased steadily over the past decade. This report describes drug-related deaths and emergency department (ED) visits among women. METHODS CDC analyzed rates of fatal drug overdoses and drug misuse- or abuse-related ED visits among women using data from the National Vital Statistics System (1999-2010) and the Drug Abuse Warning Network (2004-2010). RESULTS ...

An Insider Misuse Threat Detection and Prediction Language Georgios Vasilios Magklaras BSc (Hons) MPhil Numerous studies indicate that amongst the various types of security threats, the problem of insider misuse of IT systems can have serious consequences for the health of computing infrastructures. Although incidents of external origin are also dangerous, the insider IT misuse problem is diffi...

The recent review by Vowles et al. 5 on the rates of opioid misuse, abuse, and addiction in chronic pain is a sorely needed step in the right direction toward better defining and understanding the prevalence of opioid misuse, abuse, and addiction among individuals with chronic pain. The authors are to be applauded for both synthesizing and advocating for literature using explicit definitions of...

BACKGROUND The development of abuse deterrent formulations is one strategy for reducing prescription opioid misuse and abuse. A putative abuse deterrent formulation of oxycodone extended release (OxyContin®) was introduced in 2010. Early reports demonstrated reduced abuse and diversion, however, an analysis of social media found 32 feasible methods to circumvent the abuse deterrent mechanism. W...