نتایج جستجو برای: progressive retinal atrophy

تعداد نتایج: 225473  

Journal: :Nagoya journal of medical science 1966
M Iida R Fujiwara Y Yamamura

Recently, as diagnostic aids of neurological science, not only electromyography but also other techniques such as motor nerve conduction velocity, evoked potentials and strength-duration curve have been performed. In this paper, the first, the standard value of conduction velocities and the critical value of reduced conduction velocities in pathologic condition were discussed, because the probl...

2011
John Christoforidis Robert Ricketts Theodore Loizos Susie Chang

PURPOSE To report a case of acute quinine poisoning, document acute and chronic macular changes with optical coherence tomography imaging and fluorescein angiography (FA), and to review the literature on ocular toxicity of quinine. METHODS A 32-year-old white female presented to our Emergency Department after ingesting over 7.5 g of quinine. She underwent a complete ophthalmologic examination...

Journal: :The New England Journal of Medicine 2021

Abstract Background Type 1 spinal muscular atrophy is a rare, progressive neuromuscular disease that caused by low levels of functional survival motor neuron (SMN) protein. Risdiplam an or...

Journal: :Investigative ophthalmology & visual science 1991
J B Jonas M C Fernández G O Naumann

Parapapillary chorioretinal atrophy and decreased retinal vessel diameter occur in glaucomatous eyes. To evaluate the frequency and degree of these signs in nonglaucomatous optic neuropathy, the authors evaluated morphometrically and compared 47 patients with nonglaucomatous optic nerve atrophy from extraocular causes with 292 patients with primary open-angle glaucoma and 179 normal subjects. E...

Journal: :Contemporary clinical trials 2016
Robert J Fox Christopher S Coffey Merit E Cudkowicz Trevis Gleason Andrew Goodman Eric C Klawiter Kazuko Matsuda Michelle McGovern Robin Conwit Robert Naismith Akshata Ashokkumar Robert Bermel Dixie Ecklund Maxine Koepp Jeffrey Long Sneha Natarajan Srividya Ramachandran Thomai Skaramagas Brenda Thornell Jon Yankey Mark Agius Khurram Bashir Bruce Cohen Patricia Coyle Silvia Delgado Dana Dewitt Angela Flores Barbara Giesser Myla Goldman Burk Jubelt Neil Lava Sharon Lynch Augusto Miravalle Harold Moses Daniel Ontaneda Jai Perumal Michael Racke Pavle Repovic Claire Riley Christopher Severson Shlomo Shinnar Valerie Suski Bianca Weinstock-Gutman Vijayshree Yadav Aram Zabeti

BACKGROUND Primary and secondary progressive multiple sclerosis (MS), collectively called progressive multiple sclerosis (PMS), is characterized by gradual progression of disability. The current anti-inflammatory treatments for MS have little or no efficacy in PMS in the absence of obvious active inflammation. Optimal biomarkers for phase II PMS trials is unknown. Ibudilast is an inhibitor of m...

Journal: :medical hypothesis, discovery and innovation ophthalmology journal 0
sã­lvia mendes ophthalmology department - leiria hospital centre, portugal antã³nio campos ophthalmology department - leiria hospital centre, portugal joana campos ophthalmology department - leiria hospital centre, portugal arminda neves ophthalmology department - leiria hospital centre, portugal diana beselga ophthalmology department - leiria hospital centre, portugal cristina fernandes ophthalmology department - leiria hospital centre, portugal

this article reviews clinically relevant data regarding traumatic maculopathy (tm), frequently observed in clinical practice, especially due to sport or traffic accident injuries. it is characterized by transient gray-whitish retinal coloration and reduction of visual acuity (va) with closed, blunt object globe trauma of their prior. it may be limited to the posterior pole (berlin’s edema), o...

Journal: :Arquivos brasileiros de oftalmologia 2016
Adriana Gondim de Moura Campos Rodrigo Pessoa Cavalcanti Lira Tiago Eugenio Faria E Arantes

This case report describes the retinal optical coherence tomography (OCT) findings in a microcephalic infant with macular atrophy presumably caused by intrauterine Zika virus infection. OCT demonstrated atrophy of the outer retinal layers and choriocapillaris, including the outer nuclear layer and ellipsoid zone, associated with retinal pigment epithelium hyper-reflectivity and increased OCT pe...

Journal: :AJNR. American journal of neuroradiology 2005
Elisabetta Pagani Maria A Rocca Antonio Gallo Marco Rovaris Vittorio Martinelli Giancarlo Comi Massimo Filippi

BACKGROUND AND PURPOSE Progressive brain atrophy is a well-known feature of multiple sclerosis (MS). We characterized the spatial evolution of atrophy in different MS phenotypes. METHODS Dual-echo and T1-weighted MR images were obtained in 70 patients with MS and 10 healthy control subjects at entry and after 15 months. Within-group changes in regional atrophy were assessed by applying Struct...

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