dendrostellera lessertii (thymelaeaceae) is a toxic plant that grows in parts of iran. the anti-proliferative properties of its crude methanol extract and one of its active components, 3-hydrogenkwadaphnin (3-hk), have been established using several cancer cell lines. methods: in a further attempt to determine the mode of action, two groups of synchronously growing cells were treated with a sin...

Six cases of red cell aplasia occurring in patients with myelodysplastic syndromes (MDS) showed a diversity of clinical course and prognosis. In some patients red cell aplasia may have represented an evolution of MDS while in others autoimmune destruction of erythoblasts may have been the mechanism. A proliferative phase is seen in many of these patients, the clinical importance of which is unc...

In the developing vertebrate brain, newly born neurons migrate away from the proliferative zones. A new paper suggests that the initial phase of this migration may be propelled by the mechanical properties of the new neurons' processes rather than more conventional mechanisms of cell migration.

Three patients with bacterial endocarditis who developed renal failure have been studied by means of a radiofibrinogen catabolism study. Two were studied at the time of bacteraemia and one during the subsequent "immunological phase" of circulating immune complexes. Accelerated fibrinogen catabolism was found in all cases. Intravascular coagulation may be an important factor in the pathogenesis ...

results there was a significant increase (p < 0.05) in leptin levels on day 14 (12.75 + 5.8 ng/ml) and day 21 (12.91 + 3.2 ng/ml) for age group 18-30 years compared to day 14 (11.60 + 3.2 ng/ml) and day 21 (11.60 + 3.2 ng/ml) for age group 31-40 years. leptin was positively correlated with fsh on day 14, with lh on day 7 and day 21; likewise, with progesterone on day 21 and day 28 and with estr...