نتایج جستجو برای: promethazine
تعداد نتایج: 522 فیلتر نتایج به سال:
The objective of this investigation was the development of chitosan/xanthan polyelectrolyte complex based mucoadhesive nasal insert of promethazine hydrochloride a drug used in the treatment of motion sickness. A 32 factorial design was applied for preparing chitosan/xanthan polyelectrolyte complex and to study the effect of independent variables i.e. concentration of xanthan [X1] and concentra...
Quaternized chlorpromazine, triflupromazine, and promethazine derivatives were synthesized and examined as antitubercular agents against both actively growing and non-replicating Mycobacterium tuberculosis H37Rv. Impressively, several compounds inhibited non-replicating M. tuberculosis at concentrations equal to or double their MICs against the actively growing strain. All active compounds were...
The objective of present study was to develop effervescent tablets of promethazine (PMZ) for the treatment of emesis. Effervescent tablets were prepared by direct compression method and were optimized using 3 2 full factorial design. Amount to sodium starch glycolate(X1) and amount of sodium bicarbonate (X2) were selected as independent variables, whereas disintegration time (Y1), amount of car...
BACKGROUND The incidence of postoperative nausea and vomiting (PONV) is 50% to 80% after neurosurgery. The common prophylactic treatment for postoperative nausea and vomiting is a triple therapy of droperidol, promethazine and dexamethasone. Newer, more effectives methods of prophylaxis are being investigated. We designed this prospective, double-blind, single-center study to compare the effica...
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