Introduction: Prostate cancer (PC) is the second most commonly diagnosed in males. 68Ga-PSMA PET/CT, a non-invasive diagnostic tool to evaluate PC with prostate-specific membrane antigen (PSMA) expression, has emerged as more accurate alternative assess disease staging. We aimed identify predictors of positive PET and accuracy this technique. Materials methods: Diagnostic cross-sectional study ...

A new nucleic acid-based magnetic potentiometric aptasensing platform was designed for in situ amplified measurement of prostate-specific antigen with the catalytic hairpin assembly.

AIM Two unexplored aspects for irinotecan and cisplatin (I&C) combination chemotherapy are: actively targeting both drugs to a specific diseased cell type, and delivering both drugs on the same vehicle to ensure their synchronized entry into the cell at a well-defined ratio. In this work, the authors report the use of targeted polymeric nanoparticles (NPs) to coencapsulate and deliver I&C to ca...

BACKGROUND To characterise the association between demographic and clinical factors and levels of total prostate specific antigen (tPSA) and its molecular derivatives complexed PSA (cPSA), free PSA (fPSA) and the ratio of free to total PSA (%fPSA)] in New Zealand Maori, Pacific Islanders and Europeans, in order to determine whether reported ethnic differences in PSA can be explained by lifestyl...