detection of plasmodium vivax specific antibodies with serological tests could be a valuable tool for epidemiological researches. whereas p. vivax cannot be simply obtained in vitro, serological tests using total or semi-purified antigens are infrequently used. given this restriction, the present study investigated whether recombinant p. vivax merozoite surface protein 1 (pvmsp-1 42 kda) could ...

In the present study, a set of different benzoxazole derivatives has been synthesized from ethyl acetoacetate, ethoxymethylene malononitrile, NaNO2, and organic acids. Analytical instruments like proton NMR (1H), carbon (13C), infrared spectroscopy (IR), LC-MS mass spectrometry were used for structural characterization. Synthesized molecules evaluated In-vitro antioxidant property (DPPH assay, ...

The analysis of historical materials is an essential component cultural heritage conservation. Protein was one the most important and pervasive organic substances in ancient human societies. Through qualitative quantitative examination protein-based materials, it possible to clarify their source functions heritages, investigate manufacturing technology heritage, identify deterioration mechanism...

We developed an integrated protein assay device, "Single Molecule MicroTAS (SMM)," which enables cell lysis, protein extraction, purification, and activity assay. The assay was achieved at the single-molecule scale for a genetically engineered protein, F(1)-ATPase, which is the smallest known rotary motor. A cell lysis condition, with a wide range of applied voltages (50-250 V) and other optimi...

Antifungal agents are causing different problems in the agriculture industry. Plants are using various defense mechanisms for resistance against fungal pathogens. Some examples of these mechanisms are making physical barriers, producing chemical components and pathogenesis-related proteins such as lipid transfer protein (LTP) and Osmotin which can inhibit the growth of fungi at micro-molar conc...

aflatoxins are toxic compounds which are produced by aspergillus flavus and a. parasiticus. these toxins can be transmitted into the animal body via contaminated feed. when these toxins enter the animal body, they can penetrate into different tissues. one of the most important tissues which can be influenced by aflatoxin is the mammary gland. milk protein is one the most important factors in de...

Abstract Background CSN5, a member of Cop9 signalosome, is essential for protein neddylation. It has been supposed to serve as an oncogene in some cancers. However, the role CSN5 not investigated cervical cancer yet. Methods Data from TCGA cohorts and GEO dataset was analyzed examine expression profile clinical relevance The on cell proliferation lines, Siha Hela, through knockdown via CRISPR–C...