Most non-communicable diseases are associated with dysfunction of proteins or protein complexes. The relationship between sequence and structure has been analyzed for a long time, the analysis sequences organization in domains motifs remains an actual research area. Here, we propose mathematical method revealing hierarchical sequences. is based on pentapeptide as unit Employing frequency occurr...

bacteriorhodopsin (br) is the light harvesting and photoactive proton pump found in the membrane of a salt marsh bacteria. this protein has significant potential to use in optical computing and memory devices due to unique intrinsic physical properties of photo and bioelectric. all these features make br one of the most promising protein candidates in protein memories. protein memory is a kind ...

When the history of 20th century science is written, surely the chapter on determining the structure of molecules by X-ray crystallography, NMR, and electron microscopy will be one of the most prominent, with the structures of proteins and viruses being the culminating glory. No current book illustrates and explains these glories more effectively and concisely than Branden and Tooze’s second ed...

The analysis of the three-dimensional structure of proteins is an important topic in molecular biochemistry. Structure plays a critical role in defining the function of proteins and is more strongly conserved than amino acid sequence over evolutionary timescales. A key challenge is the identification and evaluation of structural similarity between proteins; such analysis can aid in understandin...

A method of quantitative comparison of two classi cations rules applied to protein folding problem is presented. Classi cation of proteins based on sequence homology and based on amino acid composition were compared and analyzed according to this approach. The coe cient of correlation between these classi cation methods and the procedure of estimation of robustness of the coe cient are discussed.

The validation, enrichment and organization of the data stored in PDB files is essential for those data to be used accurately and efficiently for modelling, experimental design and the determination of molecular interactions. The Iditis protein structure database has been designed to allow the widest possible range of queries to be performed across all available protein structures. The Iditis d...