The quantification of nanoparticles, particularly superparamagnetic iron oxide nanoparticles (SPIONs), both in vitro and in vivo has become highly important in recent years. Some methods, such as induced coupled plasma (ICP) spectroscopy and UV-visible chemical titration using Prussian Blue (PB), already exist however they consist of the titration of the whole iron content. These standard metho...

25 26 Glucose-6-phosphate (G6P) plays an important role in carbohydrate metabolism of all living 27 organisms. Compared to the conventional analytical methods available for estimation of G6P, the 28 biosensors having relative simplicity, specificity, low-cost and fast response time are a promising 29 alternative. We have reported a G6P biosensor based on screen-printed electrode utilizing 30 Pr...

BACKGROUND This study investigated the influence of synthetic superparamagnetic iron oxide (SPIO) on dendritic cells and provides a possible method for labeling these cells. METHODS SPIO nanoparticles were prepared, and their morphology and magnetic properties were characterized. The particles were endocytosed by dendritic cells generated from mouse bone marrow. Labeling efficiency and cellul...

BACKGROUND The purpose of this study was to evaluate the inhibitory effect of targeted folate-functionalized micelles containing superparamagnetic iron oxide nanoparticles (SPIONs) and sorafenib on human hepatic carcinoma (HepG2) cells in vitro, and to observe the feasibility of surveillance of this targeting therapeutic effect by magnetic resonance imaging. METHODS Sorafenib and SPIONs were ...

Nanoheterostructures combining Prussian blue (PB) or analogues (PBA) coordination polymers with other inorganic materials onto a single nanosystem are highly challenging and rapidly emerging class of discrete hybrid multifunctional nano-objects, where chemical physical properties can act separately in synergy. They present various morphologies compositions, including diverse combinations nanosi...

A multifunctional nanotheranostic agent was developed by conjugating both hyaluronic acid and bovine serum albumin coated CuInS2-ZnS quantum dots onto the surface of magnetic Prussian blue nanoparticles. The obtained nanoagent could serve as an efficient contrast agent to simultaneously enhance near infrared (NIR) fluorescence and magnetic resonance (MR) imaging greatly. The coexistence of magn...