Results: A total of 30 eyes with pseudoexfoliation of 28 patients underwent planned combined procedure. Sixteen (53.33%) eyes achieved 6/18 or better vision postoperatively. The mean preoperative intraocular pressure was 25 mm Hg (range, 14 to 38 mm Hg), which decreased to a mean postoperative intraocular pressure of 15.1 mm Hg (range, 8 to 18 mm Hg). Intraoperative complications occurred in 4 ...

A unique characteristic of neural stem cells is their capacity to track glioma cells that have migrated away from the main tumor mass into the normal brain parenchyma. PEX, a naturally occurring fragment of human metalloproteinase-2, acts as an inhibitor of glioma and endothelial cell proliferation, migration, and angiogenesis. In the present study, we evaluated the antitumor activity of PEX-pr...

BACKGROUND To compare life span of persons with and without ocular pseudoexfoliation syndrome (PES). METHODS The study is based on an epidemiological survey conducted in Sør-Trøndelag county, Norway, in 1985-86. All inhabitants over 64 years of age (2109 individuals) were invited. Mortality information was obtained from The Norwegian Institute of Public Health in 2014, by which time 99% of th...

Membrane type-1 matrix metalloproteinase (MT1-MMP) is a promising drug target in malignancy. The structure of MT1-MMP includes the hemopexin domain (PEX) that is distinct from and additional to the catalytic domain. Current MMP inhibitors target the conserved active site in the catalytic domain and, as a result, repress the proteolytic activity of multiple MMPs instead of MT1-MMP alone. In our ...

BACKGROUND We recently developed a novel, noninvasive method for sampling nonvolatile material from the distal airways. The method is based on the collection of endogenous particles in exhaled air (PEx). The aim of this study was to characterize the protein composition of PEx and to verify that the origin of PEx is respiratory tract lining fluid (RTLF). METHOD Healthy individuals exhaled into...

PURPOSE To study the clinical correlates of pattern of deposits over the lens in patients with pseudoexfoliation syndrome (PXF) or pseudoexfoliation glaucoma. METHODS This retrospective observational study screened 346 patients with PXF seen in glaucoma clinic of a tertiary hospital from 2011-2013. Details like pattern of deposits, location on the lens surface and pupillary abnormalities in s...

ABSTRACT Purpose: The aim of this study was to evaluate the appropriate timing capsular tension ring implantation in cases zonular weakness due pseudoexfoliation syndrome. Methods: This prospective, comparative performed at Ophthalmology Department Inonu University, Malatya, Turkey. There were 43 patients included study. Group 1 (16 patients) had early implantation, and group 2 (27 late implant...