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We present the novel prokaryotic gene finder GISMO, which combines searches for protein family domains with composition-based classification based on a support vector machine. GISMO is highly accurate; exhibiting high sensitivity and specificity in gene identification. We found that it performs well for complete prokaryotic chromosomes, irrespective of their GC content, and also for plasmids as...
The current published Figure S6C contains lanes from a single gel run that have been rearranged and spliced for the purposes of figure composition. The authors wish to correct Figure S6 to adequately show these splices by the addition of solid splice lines, and by correcting the legend for further clarity. The method of this figure composition does not affect the scientific understanding of the...
Given a scarcity of journal space, what is the optimal rule for whether an empirical finding should be published? Suppose publications inform public about policy-relevant state. Then journals publish extreme results, meaning ones that move beliefs sufficiently. This may take form one- or two-sided test comparing point estimate to prior mean, with critical values determined by cost-benefit analy...
Lexical bundles are known as important elements of coherent discourse that have been the subject of much research. While the previous research has been mainly concerned with exploring variations in the use of these word sequences across different registers and disciplines, very few studies have addressed the use of some particular groups of lexical bundles within some types of academic writing....
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