Affi liations: From the Heart Institute (Drs Marchi, Vargas, and Teixeira), University of São Paulo Medical School; and Medical College of Jundiai (Drs Marchi, Madaloso, and Carvalho). Financial nonfi nancial disclosures: The authors have reported to CHEST that no potential confl icts of interest exist with any companies organizations whose products or services may be discussed in this article....

The abnormalities of pulmonary arterial blood supply in mitral stenosis, consisting primarily of constriction of lower lobe vessels with resultant upper lobe preferential flow, was assessed by means of pulmonary angiography in 30 patients with mitral stenosis uncomplicated by other cardiac diseases. The abnormalities in blood flow correlated best with both the pulmonay artery pressure and the p...

OBJECTIVES The purposes of this study were to examine the effects of dipyridamole infusion on hemodynamic variables and to compare these changes with myocardial perfusion. BACKGROUND Dipyridamole stress testing with myocardial perfusion imaging is widely used in the assessment of patients with known or suspected coronary artery disease (CAD). Few studies, however, have correlated the hemodyna...

BACKGROUND A portosystemic stent shunt may impair cardiac function and haemodynamics. AIMS To investigate the effects of a transjugular intrahepatic portosystemic shunt (TIPS) on cardiac function and pulmonary and systemic circulation in patients with alcoholic cirrhosis. PATIENTS/METHODS 17 patients with alcoholic cirrhosis and recent variceal bleeding were evaluated by echocardiography an...

Background—A portosystemic stent shunt may impair cardiac function and haemodynamics. Aims—To investigate the eVects of a transjugular intrahepatic portosystemic shunt (TIPS) on cardiac function and pulmonary and systemic circulation in patients with alcoholic cirrhosis. Patients/Methods—17 patients with alcoholic cirrhosis and recent variceal bleeding were evaluated by echocardiography and cat...

OBJECTIVES The purpose of this study was to determine the predictors of mortality in patients with pulmonary hypertension (PH) associated with heart failure with preserved ejection fraction (HFpEF). BACKGROUND PH is commonly associated with HFpEF. The predictors of mortality for patients with these conditions are not well characterized. METHODS In a prospective cohort of patients with right...

Right ventricular adaptation to the increased pulmonary arterial load is a key determinant of outcomes in pulmonary hypertension (PH). Pulmonary vascular resistance (PVR) and total arterial compliance (C) quantify resistive and elastic properties of pulmonary arteries that modulate the steady and pulsatile components of pulmonary arterial load, respectively. PVR is commonly calculated as transp...

In order to determine the presence and extent of obstructive pulmonary vascular disease in patients with congenital heart disease, magnified cineangiograms were obtained with a catheter in the pulmonary artery wedge position in 155 infants and children undergoing cardiac catheterization. The wedge angiograms (WA) were analyzed in groups according to the pulmonary hemodynamics: group A normal pu...

Pulmonary angiogram of chronic pulmonary embolism. A 31-year-old man with progressive dyspnea and clinical evidence of pulmonary hypertension had right heart pressures as follows: right atrium, 12; right ventricle, = 98/18; pulmonary artery, 90/40; mean, 65; and pulmonary capillary wedge, 8 mm Hg. The contrast pulmonary angiogram shows occlusion of the descending left pulmonary artery and 80% s...