Chronic granulomatous disease (CGD) is a rare disorder of phagocytes, predisposes patients to bacterial and fungal infections. The main purpose of this study was to determine the clinical, radiological, pathological features, outcome and response to treatment of children with CGD. Thirteen patients with CGD, who had been referred to National Research Institute of Tuberculosis and Lung Disease (...

Nontuberculous mycobacteria (NTM) disease is a notifiable condition in Queensland, Australia. Mycobacterial isolates that require species identification are forwarded to the Queensland Mycobacterial Reference Laboratory, providing a central opportunity to capture statewide data on the epidemiology of NTM disease. We compared isolates obtained in 1999 and 2005 and used data from the Queensland n...

Obesity is one of the major epidemics of our time and its prevalence is only believed to increase over coming years. The detrimental effect of obesity on the risk of cardiovascular disease, diabetes and cancer has long been recognised and has subsequently impacted on public health policy across the globe. However, there are still gaps in our knowledge regarding the complex relationship between ...

Among 40 hospitalized infants and children with cytomegalovirus infection, 14 (35%) had interstitial pneumonitis, 4 (10%) had wheezing or tachypnoea but without x-ray evidence of classical interstitial pneumonia, the remaining 22 (55%) were free of pulmonary involvement. Most patients had tachypnoea and nonproductive cough of varying durations: those with underlying pulmonary pathology tended t...

The role of chronic nontuberculous infections as a cause of human misery and disability has not been adequately appreciated. The Initial, causative factor, primarily seemingly insignificant and justifying scant consideration, may eventually pass through a series of conditions, leading in the end to invalidism and even death. It Is my purpose In this paper briefly to sketch the course of chronic...

Encephalitis is the inflammation of brain which usually caused by viral infections, but it can be also due to other non-infectious agents. We report an interesting case anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis with Haemophilus influenzae co-infection in association severe acute respiratory syndrome coronavirus 2, without pulmonary involvement or fever.

BACKGROUND Mycobacterium avium complex (MAC) is a ubiquitous pathogen, widely distributed in the environment including water, soil and animals. It is an uncommonly encountered clinical pathogen; primarily causing pulmonary infections in patients with underlying lung disease or disseminated disease in immunocompromised hosts. Sporadically, extra-pulmonary infections have been documented includin...

pulmonary arteriovenous malformations are rare clinical entities thai are associated with right to left shunts, and are often clinically presented by the triad of dyspnea, cyanosis, and digital clubbing. currently, transcatheter embolization of fistula is gaining increasing popularity as the superior therapeutic option. in certain situations, however, surgery is preferred. two cases of direct p...

Uncontrolled diabetes is a known immunosuppressive state. It predisposes individuals to bacterial and fungal infections. The present case report demonstrates sequential infections by Klebsiella followed by tuberculosis and later development of mucormycosis in a poorly controlled diabetic patient. Timing of diagnosis is of essence because of high mortality seen with such pulmonary infections. Hi...