This study investigated the effects of electromagnetic fields on enzymes involved in purine metabolism in human peripheral blood mononuclear cells in vitro. Cells were obtained from 20 volunteers. We tested both low-energy, extremely low frequency (ELF; 100-Hz) electromagnetic fields and the Therapeutic Application of Musically Modulated Electromagnetic Fields (TAMMEFs); the latter is character...

Eight dual-flow continuous-culture fermenters were used in four replicated periods to compare the effects of diet and microbial marker on estimates of N metabolism in continuous culture of ruminal microorganisms. A basal diet was supplemented with urea and tryptone, soybean meal (SBM), lignosulfonate-treated SBM, corn gluten meal, blood meal (BM), hydrolyzed feather meal, fish meal (FM), or mea...

Hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency is an X-linked defect of purine metabolism. Clinical manifestations are usually related to the degree of enzyme deficiency: complete HPRT deficiency (Lesch-Nyhan syndrome) presenting with severe neurologic or renal symptoms, or partial HPRT deficiency (Kelley-Seegmiller syndrome) manifesting as a gout-urolithiasis syndrome. A 3-ge...

An increasing amount of information on purine metabolism suggests that there is a continual release of some purines from resting skeletal muscle (Bockman et al., 1976). During exercise, hypoxanthine and inosine release can increase substantially (Murray, 1971). Presumably, skeletal muscle must be capable of maintaining an adequate level of purines in view of an apparent loss of purine nucleosid...

Urinary stone disease (USD) is a polyetiological urological caused by both exogenous and endogenous factors, including hereditary ones. It characterized the appearance of stones in kidneys urinary tract, tendency to relapse, often with severe course. Almost 25 % consist uric acid (UA). The leading role pathogenesis urate nephrolithiasis (UN) played disorders purine metabolism, which are develop...