LC3 has been used as a marker to locate autophagosomes. However, it is also well established that LC3 can localize on various membranous structures other than autophagosomes. We recently demonstrated that the LC3 conjugation system (ATG7, ATG3, and ATG12-ATG5-ATG16L1) is required to target LC3 and IFNG (interferon, gamma)-inducible GTPases to the parasitophorus vacuole membrane (PVM) of a proti...

A new representation of 3-d object appearance from video sequences has been developed over the past several years (Pollard and Mundy, 2007; Pollard, 2008; Crispell, 2010), which combines the ideas of background modeling and volumetric multi-view reconstruction. In this representation, Gaussian mixture models for intensity or color are stored in volumetric units. This 3-d probabilistic volume mo...

Emulating a parallel machine via a collection of heterogenous independent hosts and a general-purpose local area network has obvious advantages such as cost-eeectiveness and very large aggregate processing power and memory. However, the ability of most current general-purpose local area networks to support communication-intensive parallel applications has been questionable. Today, with the emer...

The success and sustainability of an avian breeding programme depend on managing productive and unproductive pairs. Given that each breeding season can be of immeasurable importance, it is critical to resolve pair fertility issues quickly. Such problems are traditionally diagnosed through behavioural observations, egg lay history and hatch rates, with a decision to re-pair generally taking one ...

During invasion, Plasmodium, the causative agent of malaria, wraps itself in a parasitophorous vacuole membrane (PVM), which constitutes a critical interface between the parasite and its host cell. Within hepatocytes, each Plasmodium sporozoite generates thousands of new parasites, creating high demand for lipids to support this replication and enlarge the PVM. Here, a global analysis of the to...

This paper presents results of the performance tests of the PVM system over an ATM Metropolitan Area Network (MAN). PVM (Parallel Virtual Machine) is a communication package, which is considered currently a de facto standard for the development of high-performance distributed applications. ATM (Asynchronous Transfer Mode) is the emerging cell-switching technology for high-speed networks. This w...

Petascale Virtual Machines (PVM) continues to be a popular software package both for creating personal grids and for building adaptable, fault tolerant applications. We will illustrate this by describing a computational biology environment built on top of PVM that is used by researchers around the world. We will then describe or recent progress in building an even more adaptable distributed vir...

The research funded by this grant is part of an ongoing research project in heterogeneous distributed computing with the PVM system, at Emory as well as at Oak Ridge Labs and the University of Tennessee. This grant primarily supports research at Emory that continues to evolve new concepts and systems in distributed computing, but it also includes the PI’S ongoing interaction with the other grou...

This paper reports the results of studying influence surfactants (SAS) on wetting titanium dioxide in alkyd paint and varnish materials (PVM), based pentaphthalic (PPh) alkyd-urethane (AU) film-forming substances. Edge angle (?°) adhesion work (Wa) were used as criteria for assessing wettability dioxide. Three additives SAS: original product AS-1, obtained from waste oil refining (with low cost...

Programs compiled by Gambit, our Scheme compiler, achieve performance as much as twice that of the fastest available Scheme compilers. Gambit is easily ported, while retaining its high performance, through the use of a simple virtual machine (PVM). PVM allows a wide variety of machine-independent optimizations and it supports parallel computation based on the future construct. PVM conveys high-...