background treatment of helicobacter pylori (h. pylori) as a major cause of gastric diseases is of utmost concern.we aimed to assess efficacy of triple therapy (amoxicillin, clarithromycin and pantoprazole) plus probiotic yogurt (py) on eradication of h.pylori. methods total 102 h. pylori positive patients were divided to 3 groups equally and randomly. for treatment of each group amoxicillin, c...

This study presents estimates of incidence of leprosy among the familial contacts (FC) and non-familial contacts (NFC) of leprosy patients in Agra, a district endemic for leprosy. The study covers 42,113 persons followed up for 123,951.2 person years (PY) during which 77 individuals developed leprosy giving an incidence of 6.2/10,000 PY in the total leprosy-free population studied (TLPS). The i...

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants present in air and food. Among PAHs, benzo(a)pyrene(BaP), phenanthrene (PH) and pyrene (PY) are considered to be important for their toxicity or abundance. To investigate the changes of biomarkers after PAH exposure, rats were treated with BaP (150 microg/kg) alone or with PH (4,300 microg/kg) and PY (2,700 microg...

Water-dispersible and fluorescent core−shell nanorods (NRs) consisting of covalently linked poly(allyamine hydrochloride)-pyrene (PAH-Py) were synthesized and used for fabricating hybrid organic−inorganic NRs. The reaction between 1-pyrenecarboxaldehyde (Py-CHO) nanorods and PAH was driven by Schiff base formation and followed by NaBH4 reduction, and caused 28% mass loss of Py molecules at the ...

Post-translational protein modifications, such as tyrosine phosphorylation, regulate protein-protein interactions (PPIs) critical for signal processing and cellular phenotypes. We extended an established yeast two-hybrid system employing human protein kinases for the analyses of phospho-tyrosine (pY)-dependent PPIs in a direct experimental, large-scale approach. We identified 292 mostly novel p...

Chronic, low-grade inflammatory responses occur in obese adipose tissue and play a crucial role in the development of insulin resistance. Macrophages exposed to high glucose upregulate the expression of SRA, a macrophage-specific scavenger receptor. The present study investigated whether Prunus yedoensis (PY) bark extract affects the inflammatory response and scavenger receptor gene expression ...

PURPOSE To test the mechanical stability and histologic osseointegration under load-bearing conditions of 2 different materials, pyrocarbon (Py) and titanium (Ti), in a rabbit model. METHODS Proximal interphalangeal implants (9 Ti, 8 Py) were placed into rabbit knees and the animals were killed after 3 months. Subsidence was assessed by monthly x-rays. Mechanical stability was measured with a...

The changes of photosynthetic parameters, water use efficiency (WUE), fatty acid composition, chlorophyll (Chl) content, malondialdehyde (MDA) content, ATPase and acid phosphatase activities, fluoride (F) content, and leaf anatomical structure of two tea cultivars, "Pingyangtezao" (PY) and "Fudingdabai" (FD), after F treatments were investigated. The results show that net photosynthetic rate (P...

OBJECTIVE To estimate the probability of reaching the criteria for starting highly active antiretroviral therapy (HAART) in a prospective cohort of adult HIV-1 seroconverters in Abidjan, Côte d'Ivoire. METHODS We recruited participants from HIV-positive donors at the blood bank of Abidjan for whom the delay since the estimated date of seroconversion (midpoint between last negative and first p...