نتایج جستجو برای: pyridazinone

تعداد نتایج: 198  

Journal: :Journal of environmental quality 2013
John Troiano Cindy Garretson Alfredo Dasilva Joe Marade Terrell Barry

The California Department of Pesticide Regulation initiated regulations on pesticide use in 1989 to mitigate groundwater contamination by atrazine [6-chloro--ethyl-'-(1-methylethyl)-1,3,5-triazine-2,4-diamine] and subsequently for simazine (6-chloro-,'-diethyl-1,3,5-triazine-2,4-diamine), diuron ['-(3,4-dichlorophenyl)-,-dimethylurea], bromacil [5-bromo-6-methyl-3-(1-methylpropyl)-2,4(1,3)-pyri...

Journal: :European journal of pharmacology 2001
R E Santing J de Boer A Rohof N M van der Zee J Zaagsma

In a guinea pig model of allergic asthma, we investigated the effects of the selective phosphodiesterase inhibitors rolipram (phosphodiesterase 4-selective), Org 9935 (phosphodiesterase 3-selective) and Org 20241 (dual phosphodiesterase 4/phosphodiesterase 3-selective), administered by aerosol inhalation in approximately equipotent bronchodilatory doses, on allergen-induced early and late asthm...

Journal: :The Journal of pharmacology and experimental therapeutics 2004
Richard R Harris Lawrence Black Sekhar Surapaneni Teodozyj Kolasa Sandra Majest Marian T Namovic George Grayson Victoria Komater Denise Wilcox Linda King Kennan Marsh Michael F Jarvis Merrill Nuss Hugh Nellans Lee Pruesser Glenn A Reinhart Bryan Cox Peer Jacobson Andrew Stewart Michael Coghlan George Carter Randy L Bell

Nonsteriodal anti-inflammatory drugs (NSAIDs) are efficacious for the treatment of pain associated with inflammatory disease. Clinical experience with marketed selective cyclooxygenase-2 (COX-2) inhibitors (celecoxib, rofecoxib, and valdecoxib) has confirmed the utility of these agents in the treatment of inflammatory pain with an improved gastrointestinal safety profile relative to NSAID compa...

2001
TOSHITERU ISHITANI YUICHI HATTORI FUMIKA SAKURAYA HISAO ONOZUKA TAKAO MAKINO NAOYUKI MATSUDA SATOSHI GANDO OSAMU KEMMOTSU

The purpose of the present study was to investigate the effects of Ca sensitizers EMD 57033, MCI-154, and EGIS-9377 in cardiac preparations from streptozotocin-induced diabetic rats. In enzymatically dissociated ventricular myocytes loaded with the Ca probe indo 1, these Ca sensitizers caused an increase in cell shortening without a significant effect on the intracellular Ca ([Ca]i) transient. ...

2005
LESLIE R. TOWILL

Germination of Oncwk seblis L. spores is controlied by light and temperature. Temperatures of30 C can induce maximal germination in the dark to a level of 60 to 95% of that induced by a saturating dose of red light (0.38 joules/square meter) providing the spores are placed at the elevated temperature immediately after being sown. Maximum dark germination occurs with a minhmum exposure of 16 to ...

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