BACKGROUND Awareness about antibiotic resistance depends on the attitudes and information about antibiotic resistance of both patients and physicians. Persons who practice self-medication are at high risk of also self-medicating with antibiotics. The purpose of the present study was to evaluate the awareness about antibiotic resistance by investigating the practice in a group of self-medication...

The Simple Aperture Photometry (SAP) product generated by the PA (Photometric Analysis) pipeline module and the PDC (Pre-­‐search Data Conditioning) processed data are designed for automated photometry on over 160,000 stars. Although significant effort has been expended to make these products robust and reliable, they do not produce the best photometry for every target. To mitigate the impact o...

C an rural financial inclusion enhance agricultural growth? This study, using annual data over the period 1981-2014 and the ARDL bounds testing approach, captures the long run as well as the short-run dynamics of the relationship between financial inclusion and agriculture in Nigeria. The results show that usage of financial services has significant impacts on agriculture both in the...

MANY common disorders, including schizophrenia ers are affected, however, and the probable mode of disease inheritance is dominant with reduced peneand bipolar affective disorder, are highly heritatrance. That is to say inheritance of the translocation ble, yet do not exhibit simple inheritance patterns. Indiconfers a genetic predisposition to develop psychiatric vidual risk is usually attribut...

Economists and economic historians have generally understood different forms of land tenure as arrangements for the supply of labor. This paper suggests a different interpretation—that land-tenure arrangements be understood rather as arrangements for the supply of financing. The cost and availability of financing depend on the arrangements available to ensure the providers of the financing a fa...

Background to colorectal cancer Colorectal cancer is one of the three most commonly diagnosed cancers in the UK and western countries. A total of 13% of all cancers and 11% of all cancer-related deaths in the UK are attributable to colorectal cancer. This constitutes approximately 36,000 new patients and 16,000 deaths per year [1]. Systemic treatment options for patients with colorectal cancer ...

In patients with plasma cell myeloma (PCM), interphase fluorescence in situ hybridization (FISH) detects prognostically relevant genetic alterations, for example, the prognostically adverse t(4;14)(p16;q32) or 17p deletions. Furthermore, mutations of the RAS protooncogene were suggested to be associated to myeloma pathogenesis. The RAS pathway inhibitor lonafarnib combined with the proteasome i...

I N RECENT YEARS, several lines of evidence have converged to support the idea that loss of genetic information is a critical step in the pathogenesis of many types of tumors. According to this model, cells shed certain critical growth regulatory genes during their evolution from normalcy to malignancy. Such growth regulators may normally act to constrain cellular proliferation; once lost, norm...

1Department of Public Health and Cell Biology, Tot Vergata University of Rome and C.S.S. Hospital, San Giovanni Rotondo, Rome, Italy; 2Chair of Human Genetics, Catholic University of Rome, Rome, Italy PCR has been used extensively for the retrospective molecular biological studies of a wide variety of pathological archival material, inc luding air-dried or stained bone marrow smears, formalinfi...

Tyrosine kinase inhibitor (TKI)-based targeted therapy has significantly modified the outcome for patients with chronic myeloid leukemia (CML) in chronic phase. However, resistance remains a major concern in blastic phase of CML and in Philadelphia chromosome positive B-cell acute lymphoblastic leukemia (Ph+ B-ALL). Secondand third-generation TKIs have been developed to overcome resistance to f...